Title:
PYRROLIDINE DERIVATIVE SERVING AS PPAR AGONIST
Document Type and Number:
WIPO Patent Application WO/2018/010656
Kind Code:
A1
Abstract:
A pyrrolidine derivative serving as a PPAR agonist, and applications thereof in treating diseases of pathways related to a PPAR receptor, such as nonalcoholic steatohepatitis, complication fibrosis, insulin resistance, primary biliary cholangitis, dyslipidemia, hyperlipemia, hypercholesterolemia, atherosclerosis, hypertriglyceridemia, cardiovascular diseases, obesity, and other diseases. Specifically, the pyrrolidine derivative is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.
Inventors:
YUAN ZHINAI (CN)
JIANG ZHIGAN (CN)
HE HAIYING (CN)
ZHANG XIAO (CN)
WANG YAN (CN)
GAO LEILEI (CN)
GONG ZHEN (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
JIANG ZHIGAN (CN)
HE HAIYING (CN)
ZHANG XIAO (CN)
WANG YAN (CN)
GAO LEILEI (CN)
GONG ZHEN (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2017/092583
Publication Date:
January 18, 2018
Filing Date:
July 12, 2017
Export Citation:
Assignee:
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D207/06; A61K31/4025; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P5/50; A61P9/10
Domestic Patent References:
| WO2007053819A2 | 2007-05-10 | |||
| WO2002017912A1 | 2002-03-07 | |||
| WO2006097175A1 | 2006-09-21 | |||
| WO2008068423A2 | 2008-06-12 |
Other References:
See also references of EP 3486231A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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