Title:
PYRROLOBENZODIAZEPINE CONJUGATES
Document Type and Number:
WIPO Patent Application WO/2022/218973
Kind Code:
A3
Abstract:
A conjugate of formula (I) wherein Ab is a modified antibody having at least one free conjugation site on each heavy chain; D represents either group D1 or D2. D' represents either group D'1 or D'2.
Inventors:
MASTERSON LUKE (GB)
TIBERGHIEN ARNAUD CHARLES (GB)
HOWARD PHILIP WILSON (GB)
TIBERGHIEN ARNAUD CHARLES (GB)
HOWARD PHILIP WILSON (GB)
Application Number:
PCT/EP2022/059733
Publication Date:
December 22, 2022
Filing Date:
April 12, 2022
Export Citation:
Assignee:
MEDIMMUNE LTD (GB)
International Classes:
A61K47/68; A61P35/00; C07D487/04
Domestic Patent References:
| WO2020006722A1 | 2020-01-09 | |||
| WO2019224340A1 | 2019-11-28 | |||
| WO2019034764A1 | 2019-02-21 | |||
| WO2020073345A1 | 2020-04-16 | |||
| WO2018069490A1 | 2018-04-19 |
Foreign References:
| GB2581394A | 2020-08-19 |
Attorney, Agent or Firm:
MEWBURN ELLIS LLP (GB)
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