Title:
QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/002102
Kind Code:
A1
Abstract:
Provided herein are novel compounds, for example, compounds having a Formula (I), Formula (II), or Formula (III), or a pharmaceutically acceptable salt thereof. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, in inhibiting KRAS G12D in a cancer cell, and/or in treating various cancer such as pancreatic cancer, colorectal cancer, lung cancer or endometrial cancer.
Inventors:
DAI XING (CN)
WANG YAOLIN (CN)
JIANG YUEHENG (CN)
NIU HAOTAO (CN)
LIU YANQIN (CN)
YANG HONG (CN)
HAN ZIXING (CN)
WANG ZHENWU (CN)
TAO LIANGSHAN (CN)
ZHANG QIANG (CN)
SHI ZHE (CN)
WENG JIFANG (CN)
WANG YAOLIN (CN)
JIANG YUEHENG (CN)
NIU HAOTAO (CN)
LIU YANQIN (CN)
YANG HONG (CN)
HAN ZIXING (CN)
WANG ZHENWU (CN)
TAO LIANGSHAN (CN)
ZHANG QIANG (CN)
SHI ZHE (CN)
WENG JIFANG (CN)
Application Number:
PCT/CN2021/103372
Publication Date:
January 06, 2022
Filing Date:
June 30, 2021
Export Citation:
Assignee:
INVENTISBIO CO LTD (CN)
International Classes:
C07D239/94; A61K31/517; A61P35/00; C07D239/72; C07D239/80
Domestic Patent References:
| WO2021106231A1 | 2021-06-03 | |||
| WO2017172979A1 | 2017-10-05 | |||
| WO2021031952A1 | 2021-02-25 |
Foreign References:
| CN110869358A | 2020-03-06 | |||
| US20170247376A1 | 2017-08-31 | |||
| CN108779097A | 2018-11-09 | |||
| CN106488910A | 2017-03-08 |
Attorney, Agent or Firm:
KINGSOUND & PARTNERS (CN)
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