Title:
QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR LIGANDS
Document Type and Number:
WIPO Patent Application WO2001004118
Kind Code:
A3
Abstract:
A compound according to formula (I) wherein z© is a phenyl ring, a C4 to C9 heteroaromatic compound containing one or more heteroatoms, or a naphthalenyl, 5,6,7,8-tetrahydronaphthalenyl or biphenyl group; which shows high affinity for muscarinic M3 receptors (Hm3).
Inventors:
FERNANDEZ FORNER DOLORS (ES)
PRAT QUINONES MARIA (ES)
BUIL ALBERO MARIA ANTONIA (ES)
PRAT QUINONES MARIA (ES)
BUIL ALBERO MARIA ANTONIA (ES)
Application Number:
PCT/EP2000/006469
Publication Date:
July 19, 2001
Filing Date:
July 07, 2000
Export Citation:
Assignee:
ALMIRALL PRODESFARMA SA (ES)
FERNANDEZ FORNER DOLORS (ES)
PRAT QUINONES MARIA (ES)
BUIL ALBERO MARIA ANTONIA (ES)
FERNANDEZ FORNER DOLORS (ES)
PRAT QUINONES MARIA (ES)
BUIL ALBERO MARIA ANTONIA (ES)
International Classes:
A61K31/435; A61K31/439; A61K31/4745; A61P1/00; A61P1/04; A61P1/06; A61P1/12; A61P11/00; A61P11/02; A61P11/06; A61P11/08; A61P11/14; A61P13/00; A61P13/02; A61P13/06; A61P13/10; A61P27/16; A61P43/00; C07D453/02; (IPC1-7): C07D453/02; A61K31/435; A61P43/00
Foreign References:
| EP0424021A1 | 1991-04-24 | |||
| FR2012964A1 | 1970-03-27 |
Other References:
CHEMICAL ABSTRACTS, vol. 104, no. 19, 12 May 1986, Columbus, Ohio, US; abstract no. 168339g, GODOVIKOV, N. N. ET AL.: "Synthesis and muscarinolytic activity of quinuclidinyl benzilate alkyl iodides" XP002128290
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