Title:
RADIOACTIVE CARBON MICROSPHERE INJECTION, PREPARATION METHOD, AND USE
Document Type and Number:
WIPO Patent Application WO/2022/134407
Kind Code:
A1
Abstract:
Disclosed are a radioactive carbon microsphere injection, a preparation method, and a use, related to the field of pharmaceutical technology. Each 1 ml of radioactive carbon microsphere injection comprises: 0.1 to 300 mg of radioactive carbon microspheres and 1 to 0.8 ml of a hydrogel. The injection is used for the preparation of medications that treat tumors, and can be directly injected into a tumor by interventional means, allowing for direct determination, according to the administration volume, of the radioactive dosage of the radioactive carbon microspheres. Hydrogel that has reached inside of the tumor can, together with calcium ions, form a gel inside of the tumor, so that the radioactive carbon microspheres can be dispersed relatively uniformly and be limited in the tumor. The radioactive carbon microspheres provide high-dosage local radiation therapy to implement the treatment of a solid tumor. The present invention has wide application prospect in solid tumor treatment.
Inventors:
ZHAO XIAOSHENG (CN)
ZHANG CHIXIANG (CN)
MA WENLIANG (CN)
ZHANG JUN (CN)
LU JING (CN)
BAI BING (CN)
LI ZHONGPING (CN)
LIU QIANGQIANG (CN)
YU KUNRU (CN)
ZHANG SHUANG (CN)
LI ZHUOMING (CN)
LUO XIANJIN (CN)
GE QIANG (CN)
CAI JIMING (CN)
ZHANG CHIXIANG (CN)
MA WENLIANG (CN)
ZHANG JUN (CN)
LU JING (CN)
BAI BING (CN)
LI ZHONGPING (CN)
LIU QIANGQIANG (CN)
YU KUNRU (CN)
ZHANG SHUANG (CN)
LI ZHUOMING (CN)
LUO XIANJIN (CN)
GE QIANG (CN)
CAI JIMING (CN)
Application Number:
PCT/CN2021/089179
Publication Date:
June 30, 2022
Filing Date:
April 23, 2021
Export Citation:
Assignee:
CHENGDU NEW RADIOMEDICINE TECH CO LTD (CN)
International Classes:
A61K51/06; A61P35/00
Domestic Patent References:
| WO2005087274A1 | 2005-09-22 |
Foreign References:
| CN111939276A | 2020-11-17 | |||
| CN105854805A | 2016-08-17 | |||
| CN101283978A | 2008-10-15 |
Other References:
"The 13th Five-Year Plan Textbook for National Chinese Medicine Industry Higher Education Medicinal Polymer Materials Science", 1 June 2017, WINSHARE FLAGSHIP STORE, CN, ISBN: 978-7-5132-4134-2, article LIU, WEN: "VI. Sodium Alginate", pages: 113 - 115, XP009538045
Attorney, Agent or Firm:
CHENGDU CENTRAL ASIA PATENT AGENCY CO., LTD (CN)
Download PDF: