RADIOACTIVE TRANSITION METAL NITRIDE HETERO-COMPLEX

Title:

RADIOACTIVE TRANSITION METAL NITRIDE HETERO-COMPLEX

Document Type and Number:

WIPO Patent Application WO/1998/027100

Kind Code:

A1

Abstract:

One of radioactive transition metal nitride hetero-complexes which can label physiologically active substances such as peptides or hormones without impairing the activities thereof. It is composed of a radioactive transition metal nitride and two different ligands coordinating to the nitride, and is represented by the following general formula (I): (M$m(Z)N)XY, wherein the radioactive transition metal, M, is radioactive technetium or rhenium; N is nitrogen; X is a diphosphine compound or a diarsine compound; and Y is a bidentate ligand having a combination of electron-donating atoms.

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Inventors:

DUATTI ADRIANO (IT)
BOLZATI CRISTINA (IT)
UCCELLI LICIA (IT)
REFOSCO FIORENZO (IT)
TISATO FRANCESCO (IT)

Application Number:

PCT/JP1997/004626

Publication Date:

June 25, 1998

Filing Date:

December 16, 1997

Export Citation:

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Assignee:

NIHON MEDIPHYSICS CO LTD (JP)
DUATTI ADRIANO (IT)
BOLZATI CRISTINA (IT)
UCCELLI LICIA (IT)
REFOSCO FIORENZO (IT)
TISATO FRANCESCO (IT)

International Classes:

A61K51/04; C07F9/50; C07F13/00; (IPC1-7): C07F9/50; C07F9/70; C07F9/72; C07F13/00

Foreign References:

JPH07110869B2	1995-11-29
JPH05508842A	1993-12-09
JPH07500816A	1995-01-26

Other References: