Title:
RADIONUCLIDE LABEL AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/002022
Kind Code:
A1
Abstract:
A compound as represented by formula (I), or a pharmaceutically acceptable salt thereof, or an enantiomer or a diastereomer thereof, or a deuterium element substituent thereof. By means of complexing with a radionuclide, the compound can bind to a somatostatin receptor (SSTR) which is highly expressed in tumors and can be located in a SSTR positive tumor tissue with a high selectivity, thereby achieving the purpose of disease-targeted diagnosis and treatment.
Inventors:
WANG QIANQIAN (CN)
WANG YU (CN)
WU FANGZHOU (CN)
WU RAN (CN)
WANG LEI (CN)
SONG ZIHUI (CN)
LI ZHENHU (CN)
WANG MENGZHE (CN)
GUO FEIHU (CN)
HAN BEIBEI (CN)
WANG YU (CN)
WU FANGZHOU (CN)
WU RAN (CN)
WANG LEI (CN)
SONG ZIHUI (CN)
LI ZHENHU (CN)
WANG MENGZHE (CN)
GUO FEIHU (CN)
HAN BEIBEI (CN)
Application Number:
PCT/CN2021/103005
Publication Date:
January 06, 2022
Filing Date:
June 29, 2021
Export Citation:
Assignee:
BEIJING TUO JIE BIOPHARMACEUTICAL CO LTD (CN)
TIANJIN HENGRUI MEDICINE CO LTD (CN)
TIANJIN HENGRUI MEDICINE CO LTD (CN)
International Classes:
A61K51/00; A61K38/31; C07K7/06; C07K14/61
Foreign References:
| US6123916A | 2000-09-26 | |||
| CN1134159A | 1996-10-23 | |||
| US20090016989A1 | 2009-01-15 | |||
| CN104755472A | 2015-07-01 | |||
| CN108137690A | 2018-06-08 | |||
| CN105384807A | 2016-03-09 | |||
| CN110099682A | 2019-08-06 | |||
| US20070066516A1 | 2007-03-22 |
Attorney, Agent or Firm:
GE CHENG & CO., LTD (CN)
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