Title:
REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT
Document Type and Number:
WIPO Patent Application WO/2007/122847
Kind Code:
A1
Abstract:
A reagent for organic syntheses with which a chemical reaction can be conducted in a liquid phase and unnecessary compound(s) can be easily separated at low cost from the liquid phase after completion of the reaction. The reagent for organic syntheses reversibly changes from a liquid-phase state to a solid-phase state with changes in solution composition and/or solution temperature, and is for use in organic synthesis reactions. This reagent for organic syntheses facilitates process developments. With the reagent, researches on and developments of, e.g., medicines through, e.g., compound library syntheses, etc. can be accelerated. It can hence contribute to a technical innovation in the biochemical industry and chemical industry.
Inventors:
CHIBA KAZUHIRO (JP)
KIM SHOKAKU (JP)
KONO YUSUKE (JP)
KIM SHOKAKU (JP)
KONO YUSUKE (JP)
Application Number:
PCT/JP2007/052996
Publication Date:
November 01, 2007
Filing Date:
February 19, 2007
Export Citation:
Assignee:
UNIV TOKYO NAT UNIV CORP (JP)
JITSUBO CO LTD (JP)
CHIBA KAZUHIRO (JP)
KIM SHOKAKU (JP)
KONO YUSUKE (JP)
JITSUBO CO LTD (JP)
CHIBA KAZUHIRO (JP)
KIM SHOKAKU (JP)
KONO YUSUKE (JP)
International Classes:
C07B61/00; C07C41/22; C07C41/26; C07C43/225; C07C43/23; C07C67/08; C07C69/734; C07C217/84; C07C265/12; C07C273/18; C07C275/34; C07C281/20; C07D233/60; C07D487/04; C07F9/50
Domestic Patent References:
| WO2003018188A1 | 2003-03-06 |
Foreign References:
| JP2001122889A | 2001-05-08 | |||
| JP2000044493A | 2000-02-15 | |||
| JP2003183298A | 2003-07-03 | |||
| JP2005508890A | 2005-04-07 | |||
| EP1426101A1 | 2004-06-09 |
Other References:
HAYASHI K. ET AL.: "Microwave-promoted Suzuki-Miyaura coupling reactions in a cycloalkane-based thermomorphic biphasic system", TETRAHEDRON LETTERS, vol. 47, 9 January 2006 (2006-01-09), pages 171 - 174, XP005194793
AZEFU Y. ET AL.: "Facile synthesis of stable lipid analogues processing a range of alkyl groups: application to artificial glycolipids", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 10, 2002, pages 4013 - 4022, XP003012981
SATO R. ET AL.: "Synthesis of 3,4,5-tris(alkyloxy)benzyl glycosides as glycolipid analogues", JOURNAL OF CARBOHYDRATE CHEMISTRY, vol. 23, no. 6&7, 2004, pages 375 - 388, XP003012982
MARTINEZ-PALAU M. ET AL.: "Synthsis of luminescent N-arylcarbazoles by copper bronze-mediated reaction", LETTERS IN ORGANIC CHEMISTRY, vol. 1, 2004, pages 231 - 237, XP003012983
TAMIAKI H. ET AL.: "A novel protecting group for constructing combinatorial peptide libraries", BULL. CHEM. SOC. JPN., vol. 74, 2001, pages 733 - 738, XP002989508
CHIBA K. ET AL.: "A liquid-phase peptide synthesis in cyclohexane-based biphasic thermomorphic systems", CHEM. COMMUN., 2002, pages 1766 - 1767, XP008076759
YAMAGUCHI T. ET AL.: "Macroscopic spinning chirality memorized in spin-coated films of spatially designed zinc porphyrin J-aggregates", ANGEW. CHEM. INT. ED., vol. 43, 2004, pages 6350 - 6355, XP003012984
KISHIMURA A. ET AL.: "Phosphorescent organogels via "Metallophilic" interactions for reversible RGB-Color Switching", J. AM. CHEM. SOC., vol. 127, no. 1, 2005, pages 179 - 183, XP003012985
See also references of EP 2003104A4
AZEFU Y. ET AL.: "Facile synthesis of stable lipid analogues processing a range of alkyl groups: application to artificial glycolipids", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 10, 2002, pages 4013 - 4022, XP003012981
SATO R. ET AL.: "Synthesis of 3,4,5-tris(alkyloxy)benzyl glycosides as glycolipid analogues", JOURNAL OF CARBOHYDRATE CHEMISTRY, vol. 23, no. 6&7, 2004, pages 375 - 388, XP003012982
MARTINEZ-PALAU M. ET AL.: "Synthsis of luminescent N-arylcarbazoles by copper bronze-mediated reaction", LETTERS IN ORGANIC CHEMISTRY, vol. 1, 2004, pages 231 - 237, XP003012983
TAMIAKI H. ET AL.: "A novel protecting group for constructing combinatorial peptide libraries", BULL. CHEM. SOC. JPN., vol. 74, 2001, pages 733 - 738, XP002989508
CHIBA K. ET AL.: "A liquid-phase peptide synthesis in cyclohexane-based biphasic thermomorphic systems", CHEM. COMMUN., 2002, pages 1766 - 1767, XP008076759
YAMAGUCHI T. ET AL.: "Macroscopic spinning chirality memorized in spin-coated films of spatially designed zinc porphyrin J-aggregates", ANGEW. CHEM. INT. ED., vol. 43, 2004, pages 6350 - 6355, XP003012984
KISHIMURA A. ET AL.: "Phosphorescent organogels via "Metallophilic" interactions for reversible RGB-Color Switching", J. AM. CHEM. SOC., vol. 127, no. 1, 2005, pages 179 - 183, XP003012985
See also references of EP 2003104A4
Attorney, Agent or Firm:
SHOBAYASHI, Masayuki et al. (25-8 Higashi-ikebukuro 1-chome, Toshima-k, Tokyo 13, JP)
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