RECEPTOR AGONISTS - TAKEDA CHEMICAL INDUSTRIES LTD

Title:

RECEPTOR AGONISTS

Document Type and Number:

WIPO Patent Application WO/2004/067008

Kind Code:

A1

Abstract:

It is intended to provide a TGR5 receptor agonist containing a fused ring compound represented by the following general formula, its salt or a prodrug thereof: (I) wherein the ring A represents an optionally substituted aromatic ring; and the ring B’ represents a 5- to 8-membered ring having one or more substituents; which is useful in treating various diseases.

Inventors:

ITOH FUMIO (JP)
HINUMA SHUJI (JP)
KANZAKI NAOYUKI (JP)
MIKI TAKASHI (JP)
KAWAMATA YUJI (JP)
OI SATORU (JP)
TAWARAISHI TAISUKE (JP)
ISHICHI YUJI (JP)
HIROHASHI MARIKO (JP)

Application Number:

PCT/JP2004/000706

Publication Date:

August 12, 2004

Filing Date:

January 27, 2004

Export Citation:

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Assignee:

TAKEDA CHEMICAL INDUSTRIES LTD (JP)
ITOH FUMIO (JP)
HINUMA SHUJI (JP)
KANZAKI NAOYUKI (JP)
MIKI TAKASHI (JP)
KAWAMATA YUJI (JP)
OI SATORU (JP)
TAWARAISHI TAISUKE (JP)
ISHICHI YUJI (JP)
HIROHASHI MARIKO (JP)

International Classes:

A61K31/4353; A61K31/5513; A61K31/553; A61P1/04; A61P1/18; A61P3/04; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P11/06; A61P13/12; A61P19/02; A61P29/00; A61P31/00; A61P37/06; A61P37/08; A61P43/00; C07D267/14; (IPC1-7): A61K31/553; A61K31/4353; A61K31/5513; A61K45/00; A61P1/04; A61P1/18; A61P3/04; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P11/06; A61P13/12; A61P19/02; A61P29/00; A61P31/00; A61P37/06; A61P37/08; A61P43/00; C07D243/14; C07D267/14; C07D401/06; C07D401/12; C07D405/06; C07D409/06; C07D413/06; C07D413/10; C07D413/12; C07D417/06; C07D498/04; G01N33/15; G01N33/50

Domestic Patent References:

WO2003002147A1	2003-01-09
WO2001055121A1	2001-08-02

Foreign References:

JPH11209356A	1999-08-03
JPS63238069A	1988-10-04
US6150357A	2000-11-21
JP2000502356A	2000-02-29

Other References: