Title:
RECEPTOR FUNCTION REGULATING AGENT
Document Type and Number:
WIPO Patent Application WO/2006/038738
Kind Code:
A1
Abstract:
A GPR40 receptor function regulating agent, comprising a condensed imidazole compound, or salt or prodrug thereof, represented by the formula: (I) (wherein the characters are as defined in the description). This GPR40 receptor function regulating agent is useful as a preventive/therapeutic agent for obesity, hyperinsulinemia, type II diabetes, etc.
Inventors:
ITOH FUMIO (JP)
SASAKI SATOSHI (JP)
MIYAZAKI JUNICHI (JP)
SUZUKI NOBUHIRO (JP)
SASAKI SATOSHI (JP)
MIYAZAKI JUNICHI (JP)
SUZUKI NOBUHIRO (JP)
Application Number:
PCT/JP2005/018908
Publication Date:
April 13, 2006
Filing Date:
October 07, 2005
Export Citation:
Assignee:
TAKEDA PHARMACEUTICAL (JP)
ITOH FUMIO (JP)
SASAKI SATOSHI (JP)
MIYAZAKI JUNICHI (JP)
SUZUKI NOBUHIRO (JP)
ITOH FUMIO (JP)
SASAKI SATOSHI (JP)
MIYAZAKI JUNICHI (JP)
SUZUKI NOBUHIRO (JP)
International Classes:
A61K31/4184; A61K31/422; A61K31/437; A61K31/4439; A61K31/454; A61P1/18; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/50; A61P7/02; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P25/00; A61P25/24; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P37/02; A61P43/00; C07D235/26; C07D235/28; C07D235/30; C07D401/04; C07D401/12; C07D401/14; C07D405/10; C07D413/10; C07D471/04
Domestic Patent References:
WO2004014369A1 | 2004-02-19 | |||
WO2003006438A1 | 2003-01-23 | |||
WO2002088107A1 | 2002-11-07 | |||
WO2003088967A1 | 2003-10-30 |
Foreign References:
JP2002522431A | 2002-07-23 |
Other References:
SHINOZAKI K ET AL: "Stress and vascular responses: oxidative stress and endothelial dysfunction in the insulin-resistant state.", J PHARMACOL SCI., vol. 91, no. 3, 2003, pages 187 - 191, XP002993686
Attorney, Agent or Firm:
Takashima, Hajime (Osaka Midosuji Bldg. 1-1, Fushimimachi
4-chome, Chuo-k, Osaka-shi Osaka 44, JP)
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