Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
RECEPTOR-INTERACTING PROTEIN 1 INHIBITORS INCLUDING PIPERAZINE HETEROCYCLIC AMIDE UREAS
Document Type and Number:
WIPO Patent Application WO/2021/233394
Kind Code:
A1
Abstract:
The present disclosure provides compounds including piperazine heterocyclic amide urea compounds that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.

More Like This:
JP4385414Amide or amine derivative
JPS62228064PYRAZOLINE DERIVATIVE, ITS PRODUCTION AND INSECTICIDAL/ MITECIDAL AGENT CONTAINING THE SAME
WO/2002/048100THIOSULPHONIC S-ESTERS AS MATERIAL PROTECTIVE AGENT
Inventors:
SU YANING (CN)
ZHANG ZHIYUAN (CN)
ZHANG ZHAOLAN (CN)
XU YANPING (CN)
Application Number:
PCT/CN2021/094986
Publication Date:
November 25, 2021
Filing Date:
May 20, 2021
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SIRONAX LTD (GB)
SU YANING (CN)
International Classes:
C07D231/06; A61K31/4155; A61P43/00; C07D295/16
Domestic Patent References:
WO2020103884A12020-05-28
WO2019224773A12019-11-28
WO2003079973A22003-10-02
Foreign References:
CN107624111A2018-01-23
CN102316735A2012-01-11
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: BELT STATE MONITORING APPARATUS AND METHOD FOR SELF-POWERED BELT CONVEYOR

Next Patent: COMMUNICATION METHOD AND APPARATUS, AND COMPUTER-READABLE STORAGE MEDIUM