Title:
RECOMBINANT BACTERIUM FOR PRODUCING L-LYSINE, CONSTRUCTION METHOD THEREOF, AND METHOD FOR PRODUCING L-LYSINE
Document Type and Number:
WIPO Patent Application WO/2019/085445
Kind Code:
A1
Abstract:
A recombinant bacterium for producing L-lysine, a construction method thereof, and a method for producing L-lysine by using the recombinant bacterium. The recombinant bacterium has increased expression and/or activity of asparaginase compared to a starting bacterium.
Inventors:
WEN TINGYI (CN)
ZHANG CHEN (CN)
SHANG XIULING (CN)
CHAI XIN (CN)
ZHANG YUN (CN)
LIU SHUWEN (CN)
WANG GUOQIANG (CN)
LI ZHONGCAI (CN)
ZHANG CHEN (CN)
SHANG XIULING (CN)
CHAI XIN (CN)
ZHANG YUN (CN)
LIU SHUWEN (CN)
WANG GUOQIANG (CN)
LI ZHONGCAI (CN)
Application Number:
PCT/CN2018/087894
Publication Date:
May 09, 2019
Filing Date:
May 22, 2018
Export Citation:
Assignee:
BEIJING ZHONGKE EPPEN BIOTECH CO LTD (CN)
INST MICROBIOLOGY CAS (CN)
INST MICROBIOLOGY CAS (CN)
International Classes:
C12N1/21; C12N15/64; C12N15/69; C12P13/08; C12R1/01; C12R1/645
Foreign References:
| CN1989256A | 2007-06-27 | |||
| US20110008858A1 | 2011-01-13 |
Other References:
XU, JIANZHONG: "Breeding L-lysine Hyper Producer by Corynebacterium Glutamicum based on Metabolic Engineering", CHINE DOCTORAL DISSERT. DATABASE (BASIS SCIENCES), no. 3, 15 March 2015 (2015-03-15), XP009518215
JOSEF CREMER: "Control of the Lysine Biosynthesis Sequence in Corynebacte- rium glutamicum as Analyzed by Overexpression of the Individual Correspon- ding Genes", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 30 June 1991 (1991-06-30), pages 1746 - 1752, XP000616281, ISSN: 1432-0614
JOSEF CREMER: "Control of the Lysine Biosynthesis Sequence in Corynebacte- rium glutamicum as Analyzed by Overexpression of the Individual Correspon- ding Genes", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 30 June 1991 (1991-06-30), pages 1746 - 1752, XP000616281, ISSN: 1432-0614
Attorney, Agent or Firm:
BEIJING LAWSING IP FIRM (CN)
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