REGULATION OF HUMAN P2Y8-LIKE G PROTEIN-COUPLED RECEPTOR

Title:

REGULATION OF HUMAN P2Y8-LIKE G PROTEIN-COUPLED RECEPTOR

Document Type and Number:

WIPO Patent Application WO2002000700

Kind Code:

A3

Abstract:

Reagents which regulate human P2Y8-like G protein-coupled receptor can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, infections such as bacterial, fungal, protozoan, and viral infections, particularly those caused by HIV viruses, pain, cancers, anorexia, bulimia, asthma, CNS diseases such as Parkinson's disease, acute heart failure, hypotension, hypertension, urinary retention, osteoporosis, diabetes, angina pectoris, myocardial infarction, ulcers, asthma, inflammation, allergies, multiple sclerosis, benign prostatic hypertrophy, and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, several mental retardation, and dyskinesias, such as Huntington's disease and Tourett's syndrome.

More Like This:

WO/2001/014420	NOVEL MEMBERS OF THE PLEXIN FAMILY AND USES THEREOF
WO/2020/169974	HYPOXIA-RESPONSIVE CHIMERIC ANTIGEN RECEPTORS
JPH10510709	INDUSTRIAL APPLICABILITY A method for altering feeding behavior, a compound useful for the method, and a DNA encoding an atypical neuropeptide Y / peptide YY receptor (Y5) in the hypothalamus.

Inventors:

RAMAKRISHNAN SHYAM (US)

Application Number:

PCT/EP2001/007204

Publication Date:

July 04, 2002

Filing Date:

June 25, 2001

Export Citation:

Click for automatic bibliography generation Help

Assignee:

BAYER AG (DE)
RAMAKRISHNAN SHYAM (US)

International Classes:

C07K14/705; C12N15/12; A61K38/00; (IPC1-7): C12N15/12; C07K14/705; C07K16/28; C12N9/00; C12N15/11; C12N15/62; C12Q1/68; G01N33/50; G01N33/53

Domestic Patent References:

WO2000011170A1	2000-03-02
WO2000020438A1	2000-04-13
WO1997019170A1	1997-05-29
WO2001025280A1	2001-04-12

Other References:

ADRIAN K ET AL.: "Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells", BIOCHIMICA ET BIOPHYSICA ACTA. GENE STRUCTURE AND EXPRESSION, vol. 1492, no. 1, 21 June 2000 (2000-06-21), pages 127 - 138, XP004275665, ISSN: 0167-4781
DATABASE EM_EST EMBL; 16 February 1998 (1998-02-16), NCI-CGAP: "ns28c04.s1 NCI_CGAP_GCB1 Homo sapiens cDNA clone IMAGE:1184934 3' similar to TR:P79928 P79928 P2Y8 NUCLEOTIDE RECEPTOR. ;, mRNA sequence.", XP002195829
DATABASE SWALL EMBL; 1 November 1997 (1997-11-01), BOGDANOV Y D ET AL.: "P2Y PURINOCEPTOR 8 (P2Y8) Xenopus laevis (African clawed frog)", XP002195830
WILSON S ET AL.: "Orphan G-protein-coupled receptors: the next generation of drug targets?", BRITISH JOURNAL OF PHARMACOLOGY, vol. 125, no. 7, December 1998 (1998-12-01), pages 1387 - 1392, XP001010584, ISSN: 0007-1188

Download PDF:

View/Download PDF PDF Help

Previous Patent: A NOVEL POLYPEPTIDE-HOMO PHOSPHORYL TRANSPORT PROTEIN 12 AND POLYNUCLEOTIDE ENCODING SAID POLYPEPTID...

Next Patent: REGULATION OF HUMAN GONADOTROPIN RELEASING HORMONE RECEPTOR-LIKE G PROTEIN-COUPLED RECEPTOR