Title:
REMEDIES FOR DISEASES TO BE APPLIED TO EYE
Document Type and Number:
WIPO Patent Application WO/2004/091630
Kind Code:
A1
Abstract:
Remedies for various diseases which are in the form of eye-drops, eye washes, etc. containing sex steroid hormones such as estrogen or its metabolite, derivatives thereof, structural analogs thereof, estrogen agonists, SERM or non-feminizing estrogen (non-hormonal estrogen). Thus, remedies for diseases to be applied to the eye which have excellent therapeutic effects with relieved side effects can be provided.
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Inventors:
OKAMOTO SHINSEIRO
Application Number:
PCT/JP2004/005479
Publication Date:
October 28, 2004
Filing Date:
April 16, 2004
Export Citation:
Assignee:
ADVANCED MEDICINE RES INST (JP)
OKAMOTO SHINSEIRO
OKAMOTO SHINSEIRO
International Classes:
A61K9/00; A61K31/56; A61K31/565; A61K31/568; A61P5/00; A61P5/24; A61P25/00; A61P25/14; A61P25/18; A61P25/26; A61P25/28; A61P27/02; A61P27/06; A61P27/10; A61P27/12; A61P27/14; A61P37/00; (IPC1-7): A61K31/56; A61K31/565; A61K31/568; A61K45/00; A61K9/06; A61K9/08; A61K47/40; A61P5/00; A61P27/02; A61P27/06; A61P27/10; A61P27/12; A61P25/00; A61P25/18; A61P37/00
Domestic Patent References:
WO2001041757A1 | 2001-06-14 | |||
WO2002040032A2 | 2002-05-23 |
Foreign References:
JP2003505345A | 2003-02-12 | |||
US5521168A | 1996-05-28 | |||
JPH06508362A | 1994-09-22 | |||
JP2002539166A | 2002-11-19 | |||
JPH07501081A | 1995-02-02 | |||
JP2000514442A | 2000-10-31 | |||
JPH06511513A | 1994-12-22 | |||
JPH029825A | 1990-01-12 |
Other References:
XIA S. ET AL.: "The Estrogen Receptor Is Not Essential for All Estrogen Neuroprotection: New Evidence from a New Analog", NEUROBIOLOGY OF DISEASE, vol. 9, 2002, pages 282 - 293, XP002980079
SULLIVAN D.A. ET AL.: "Androgen Stimulation of Lacrimal Gland Function in Mouse Models of Sjögren's Syndrome", J. STEROID BIOCHEM. MOLEC. BIOL., vol. 60, no. 3-4, 1997, pages 237 - 245, XP002980080
SULLIVAN D.A. ET AL.: "Androgen Stimulation of Lacrimal Gland Function in Mouse Models of Sjögren's Syndrome", J. STEROID BIOCHEM. MOLEC. BIOL., vol. 60, no. 3-4, 1997, pages 237 - 245, XP002980080
Attorney, Agent or Firm:
Tsukuni, Hajime (22-12 Toranomon 1-chom, Minato-ku Tokyo 01, JP)
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