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Title:
REMEDIES
Document Type and Number:
WIPO Patent Application WO/2002/083660
Kind Code:
A1
Abstract:
Drugs, foods, drinks and feeds containing as the active ingredient compounds having coumarin and/or chroman skeletons which have an effect of enhancing NGF production and thus are efficacious in treating, ameliorating or preventing diseases with a need for enhanced NGF production. Because of having neither toxicity nor any side effects, the active compounds are usable in safely and appropriately treating the above diseases.

Inventors:
OHNOGI HIROMU (JP)
SHIRAGA MASAHIRO (JP)
SAGAWA HIROAKI (JP)
KATO IKUNOSHIN (JP)
Application Number:
PCT/JP2002/003037
Publication Date:
October 24, 2002
Filing Date:
March 28, 2002
Export Citation:
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Assignee:
TAKARA BIO INC (JP)
OHNOGI HIROMU (JP)
SHIRAGA MASAHIRO (JP)
SAGAWA HIROAKI (JP)
KATO IKUNOSHIN (JP)
International Classes:
A61K31/366; A61K31/37; A61K31/7048; A61P25/28; A61P27/02; A61P43/00; C07H17/04; C07H17/075; (IPC1-7): C07D311/18; C07D311/20; C07H17/075; C07H17/04; A61K31/37; A61K31/7048; A61K31/366; A61P25/28; A61P43/00; A23L1/30; A23L2/38; A23K1/16
Domestic Patent References:
WO2001076614A12001-10-18
WO2001076580A12001-10-18
Foreign References:
JPH04210643A1992-07-31
EP0515917A11992-12-02
Other References:
MURASE KATSUHITO ET AL.: "Tobacco tar components that stimulate nerve growth factor (NGF) synthesis/secretion of mouth astroglial cells in culture", BIOSCI. BIOTECH. BIOCHEM., vol. 58, no. 5, 1994, pages 900 - 905, XP002953139
VELASCO LARA ET AL.: "Delta9-tetrahydrocannabinol increases nerve growth factor production by prostate PC-3 cells", EUR. J. BIOCHEM., vol. 268, February 2001 (2001-02-01), pages 531 - 535, XP002953140
See also references of EP 1386919A4
Attorney, Agent or Firm:
Hosoda, Yoshinori c/o Hosoda International Patent Office (OMM Building 5th Floor P.O.Box 26, 7-31, Otemae 1-chome, Chuo-k, Osaka-shi Osaka, JP)
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