Title:
REMOTELY TRIGGERED THERAPY
Document Type and Number:
WIPO Patent Application WO/2020/172618
Kind Code:
A3
Abstract:
This disclosure provides particles that are suitable for remotely-triggered therapy for cancer and microbial infection. In an embodiment, this disclosure provides a particle heater comprising a carrier admixed with a material that interacts with an exogenous source; wherein the material absorbs and converts the energy from the exogenous source into heat, then the heat travels outside the particle heater to induce localized hyperthermia at a temperature sufficient to selectively kill unwanted cells, and further wherein the particle heater structure is constructed such that it passes the Extractable Cytotoxicity Test.
Inventors:
HORNER GLENN (US)
RAI PRAKASH (US)
AGRAWAL SATISH (US)
PARKER BETHANY (US)
RAI PRAKASH (US)
AGRAWAL SATISH (US)
PARKER BETHANY (US)
Application Number:
PCT/US2020/019348
Publication Date:
October 22, 2020
Filing Date:
February 21, 2020
Export Citation:
Assignee:
BAMBU VAULT LLC (US)
HORNER GLENN (US)
RAI PRAKASH (US)
AGRAWAL SATISH (US)
HORNER GLENN (US)
RAI PRAKASH (US)
AGRAWAL SATISH (US)
International Classes:
A61K9/51; A61K41/00; A61N2/08; A61P31/00; A61P35/00; B82Y5/00
Domestic Patent References:
| WO2011018513A1 | 2011-02-17 | |||
| WO2017086794A1 | 2017-05-26 |
Foreign References:
| US7968117B1 | 2011-06-28 | |||
| US20170065523A1 | 2017-03-09 | |||
| US20030198262A1 | 2003-10-23 | |||
| US4338578A | 1982-07-06 | |||
| US20180243227A1 | 2018-08-30 | |||
| US20140154325A1 | 2014-06-05 |
Other References:
GISKE ET AL.: "Clinical and economic impact of common multidrug-resistant gram-negative bacilli", ANTIMICROB AGENTS CHEMOTHER, vol. 52, 10 December 2007 (2007-12-10), pages 813 - 821, XP055749017, DOI: 10.1128/AAC.01169-07
JOYCE ET AL.: "Antimicrobial spectrum of the antitumor agent, cisplatin", J ANTIBIOT, vol. 63, 23 June 2010 (2010-06-23), pages 530 - 532, XP055055686, DOI: 10.1038/ja.2010.64
JOYCE ET AL.: "Antimicrobial spectrum of the antitumor agent, cisplatin", J ANTIBIOT, vol. 63, 23 June 2010 (2010-06-23), pages 530 - 532, XP055055686, DOI: 10.1038/ja.2010.64
Attorney, Agent or Firm:
CHAI, Deping et al. (US)
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