Title:
RETINOIC ACID RECEPTOR ANTAGONISTS AS PROMOTERS OF ANGIOGENESIS
Document Type and Number:
WIPO Patent Application WO2002022113
Kind Code:
A3
Abstract:
Methods and compositions for treating various disorders by administering a therapeutically effective amount of a retinoic acid receptor antagonist to promote angiogenesis are provided. Also provided are methods for obtaining additional retinoic acid receptor antagonists for use as therapeutic agents to promote angiogenesis.
Inventors:
IOTZOVA VIOLETTA (US)
RECZEK PETER (US)
RECZEK PETER (US)
Application Number:
PCT/US2001/028512
Publication Date:
March 13, 2003
Filing Date:
September 13, 2001
Export Citation:
Assignee:
BRISTOL MYERS SQUIBB CO (US)
IOTZOVA VIOLETTA (US)
RECZEK PETER (US)
IOTZOVA VIOLETTA (US)
RECZEK PETER (US)
International Classes:
A61K31/19; A61K31/203; A61P9/08; A61P11/06; A61P11/08; A61P19/08; (IPC1-7): A61K31/203; A61P9/08; A61P11/06; A61P11/08; A61P19/08
Domestic Patent References:
| WO1998036746A1 | 1998-08-27 | |||
| WO1998046228A1 | 1998-10-22 |
Foreign References:
| US6083973A | 2000-07-04 |
Other References:
SCHMEISSER A ET AL: "[Therapeutic neoangiogensis]", ZEITSCHRIFT FUR KARDIOLOGIE. GERMANY APR 1999, vol. 88, no. 4, April 1999 (1999-04-01), pages 241 - 244, XP002207685, ISSN: 0300-5860
STEGMANN THOMAS J ET AL: "Induction of myocardial neoangiogenesis by human growth factors. A new therapeutic option in coronary heart disease", BIOSIS, XP002186308
STEGMANN THOMAS J ET AL: "Induction of myocardial neoangiogenesis by human growth factors. A new therapeutic option in coronary heart disease", BIOSIS, XP002186308
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