Title:
REVERSE-MICELLAR DELIVERY SYSTEM FOR CONTROLLED TRANSPORTATION AND ENHANCED ABSORPTION OF AGENTS
Document Type and Number:
WIPO Patent Application WO2003051333
Kind Code:
B1
Abstract:
The invention can be summarized as follows. The present invention provides a reverse-micellar delivery system for enhanced absorption of an agent of interest across biological membranes such as the gastro-intestinal tract of mammals. The reverse-micelles comprise at least one ionic amphipathic compound, and at least one polar active agent ionizable in aqueous or physiological media. The delivery system facilitates transportation of the agent across the gastro-intestinal tract or other membranes and enhances the in-vivo release and availability of the agent(s) of interest within a fluid environment.
Inventors:
MACGREGOR ALEXANDER (CA)
Application Number:
PCT/CA2002/001918
Publication Date:
September 12, 2003
Filing Date:
December 13, 2002
Export Citation:
Assignee:
MACGREGOR ALEXANDER (CA)
International Classes:
A61K9/107; A61K9/16; A61K9/10; A61K9/20; A61K9/48; A61K31/155; A61K31/195; A61K31/34; A61K31/401; A61K45/00; A61K47/12; A61K47/18; A61K47/20; A61P1/04; A61P3/02; A61P3/10; A61P3/14; A61P5/00; A61P7/10; A61P7/12; A61P9/00; A61P9/12; A61P11/08; A61P13/00; A61P15/00; A61P15/18; A61P19/02; A61P21/00; A61P21/02; A61P23/02; A61P25/02; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/24; A61P27/02; A61P29/00; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P33/02; A61P33/04; A61P33/06; A61P43/00; (IPC1-7): A61K9/107; A61K9/20
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