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Title:
RHESUS MONKEY BOMBESIN RECEPTOR SUBTYPE-3 (BRS-3), NUCLEOTIDES ENCODING SAME, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2004093785
Kind Code:
A3
Abstract:
A rhesus monkey bombesin receptor subtype-3 has been isolated, cloned and sequenced. This receptor is characteristic of the G-protein family of receptors. Isolated rhesus monkey bombesin receptor subtype-3 may be used to screen and identify novel bombesin receptor modulators that may contribute to the regulation of endocrine processes, metabolism, or the cell cycle. Such compounds may be used in the treatment of conditions that result from deregulated expression of bombesin receptor subtype-3.

Inventors:
TAN CARINA P (US)
HOWARD ANDREW D (US)
SANO HIDEKI (JP)
Application Number:
PCT/US2004/011473
Publication Date:
May 06, 2005
Filing Date:
April 14, 2004
Export Citation:
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Assignee:
MERCK & CO INC (US)
BANYU PHARMA CO LTD (JP)
TAN CARINA P (US)
HOWARD ANDREW D (US)
SANO HIDEKI (JP)
International Classes:
C07H21/04; C07K14/47; C07K14/705; C12N15/12; C12N15/63; G01N33/566; G01N33/567; A61K; (IPC1-7): C12N15/12; C07H21/04; C07K14/47; C12N15/63; G01N33/566; G01N33/567
Foreign References:
US6143521A2000-11-07
Other References:
SANO H.: "Characterization of the bombesin-like peptide receptor family in primates", vol. 84, July 2004 (2004-07-01), pages 139 - 146, XP004519111
See also references of EP 1620555A4
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