Title:
THE RNA INTERACTOME OF POLYCOMB REPRESSIVE COMPLEX 1 (PRC1)
Document Type and Number:
WIPO Patent Application WO/2016/149455
Kind Code:
A3
Abstract:
This invention relates to polycomb-associated RNAs, libraries and fragments of those RNAs, inhibitory nucleic acids and methods and compositions for targeting RNAs, and methods of use thereof.
Inventors:
LEE JEANNIE T (US)
ROSENBERG MICHAEL (US)
KESNER BARRY (US)
ROSENBERG MICHAEL (US)
KESNER BARRY (US)
Application Number:
PCT/US2016/022778
Publication Date:
November 03, 2016
Filing Date:
March 17, 2016
Export Citation:
Assignee:
MASSACHUSETTS GEN HOSPITAL (US)
International Classes:
C12N15/113; A61K31/7105; A61K31/712; A61K31/7125; C07H21/02; C12N15/115
Domestic Patent References:
| WO2007078599A2 | 2007-07-12 |
Foreign References:
| US20140142160A1 | 2014-05-22 | |||
| US20140162894A1 | 2014-06-12 |
Other References:
LIYANAGE, VRB ET AL.: "DNA Modifications: Function and Applications in Normal and Disease States.", BIOLOGY., vol. 3, 2014, pages 670 - 723, XP055326226
JACOB, CO ET AL.: "Identification of IRAK 1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 106, no. 15, April 2009 (2009-04-01), pages 6256 - 6261, XP055326227
JACOB, CO ET AL.: "Identification of IRAK 1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 106, no. 15, April 2009 (2009-04-01), pages 6256 - 6261, XP055326227
Attorney, Agent or Firm:
DEYOUNG, Janice Kugler et al. (P.O. Box 1022Minneapolis, Minnesota, US)
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