Title:
SALT OF DIOXANE QUINOLINE COMPOUND, CRYSTAL FORM THEREOF, PREPARATION METHODS THEREFOR AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/094016
Kind Code:
A1
Abstract:
The present invention provides a salt of a dioxane quinoline compound, a crystal form thereof, preparation methods therefor and uses thereof. Specifically, the present invention relates to N-(3-fluoro-4-((5-(3-morpholinopropoxy) -2,3-dihydro-[1,4] dioxano[2,3-f] quinolin-10-yl) oxy) phenyl)-N-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, a crystal form thereof and preparation methods therefor, and uses in the preparation of a drug as an inhibitor of tyrosine kinases (e.g. VEGFR -2 and c-MET, etc.). Formula (I).
Inventors:
ZHANG QIANG (CN)
XU JUN (CN)
JI LINGTAO (CN)
XU JUN (CN)
JI LINGTAO (CN)
Application Number:
PCT/CN2023/128656
Publication Date:
May 10, 2024
Filing Date:
October 31, 2023
Export Citation:
Assignee:
BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN)
International Classes:
C07D491/056; A61K31/519; A61P35/00
Domestic Patent References:
| WO2019154133A1 | 2019-08-15 |
Foreign References:
| CN108503650A | 2018-09-07 |
Attorney, Agent or Firm:
LIU , SHEN & ASSOCIATES (CN)
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