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Title:
SALTS AND SOLID FORMS OF A COMPOUND HAVING APJ RECEPTOR ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2024/099382
Kind Code:
A1
Abstract:
The present disclosure relates to salts and solid forms of a compound that modulates APJ receptor activity, and their use as a therapeutic agent for treating diseases disorders, or conditions associated with repressed or impaired APJ receptor signaling, such as pulmonary arterial hypertension (PAH).

Inventors:
CHEN LIBO (CN)
JIANG XINGLONG (US)
Application Number:
PCT/CN2023/130583
Publication Date:
May 16, 2024
Filing Date:
November 09, 2023
Export Citation:
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Assignee:
ANNAPURNA BIO INC (US)
CHEN LIBO (CN)
International Classes:
C07D487/04; A61K31/4985; A61P9/00; A61P31/12; A61P37/00; C07C215/40
Domestic Patent References:
WO2020073011A12020-04-09
WO2020073011A12020-04-09
Other References:
"THE COMPLETE BLOG FOR THE PREPARATION OF PHARMACEUTICAL SALTS", INTERNET CITATION, 11 February 2008 (2008-02-11), pages 1 - 10, XP002513555, Retrieved from the Internet [retrieved on 20090204]
"Handbook of Pharmaceutical Salts - Properties, Selection, and Use", 1 January 2002, article P. HEINRICH STAHL ET AL: "usage frequency of acids and bases for forming drug salts", pages: 329 - 350, XP055969250
MINO R CAIRA ED - MONTCHAMP JEAN-LUC: "CRYSTALLINE POLYMORPHISM OF ORGANIC COMPOUNDS", TOPICS IN CURRENT CHEMISTRY; [TOPICS IN CURRENT CHEMISTRY], SPRINGER, BERLIN, DE, vol. 198, 1 January 1998 (1998-01-01), pages 163 - 208, XP001156954, ISSN: 0340-1022, [retrieved on 19990226], DOI: 10.1007/3-540-69178-2_5
"Remington: The Science and Practice of Pharmacy", 2012, PHARMACEUTICAL PRESS
COQUEREL ET AL., CRITICAL CARE, vol. 22, 2018, pages 10
GERSTEIN MCHOTHIA C, PROC NATI ACAD SCI, no. 19, 1996, pages 10167 - 10172
Attorney, Agent or Firm:
WU, FENG & ZHANG (CN)
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