Title:
SAMPLE TEST METHOD, TEST KIT FOR GYNECOLOGICAL CANCER AND PRECANCEROUS LESION THEREOF, AND MEDICINE
Document Type and Number:
WIPO Patent Application WO/2024/034606
Kind Code:
A1
Abstract:
Provided are: a simple and highly accurate sample test method which can be applied to the evaluation of the presence or absence of at least one selected from the group consisting of a gynecological cancer and a precancerous lesion thereof, the evaluation of the prognosis of a gynecological cancer patient, or the evaluation of the degree of malignancy of a gynecological cancer; a test kit which can be used for the test method; and a medicine for treating or preventing a gynecological cancer, which is intended to be administered to a subject detected by the test method. A sample test method is employed, the method comprising a step (A) for measuring the concentration of a free fatty acid in a sample from a subject and a step (B) for evaluating the possibility that the subject would have a of gynecological cancer on the basis of the concentration of the free fatty acid obtained in the step (A).
Inventors:
KATOH YUKI (JP)
KAWANA KEI (JP)
KUBO AKIKO (JP)
KAWANA KEI (JP)
KUBO AKIKO (JP)
Application Number:
PCT/JP2023/028921
Publication Date:
February 15, 2024
Filing Date:
August 08, 2023
Export Citation:
Assignee:
UNIV NIHON (JP)
UNIV KEIO (JP)
UNIV KEIO (JP)
International Classes:
G01N33/50; A61K45/00; A61P35/00; G01N33/92
Domestic Patent References:
| WO1994006014A1 | 1994-03-17 |
Foreign References:
| JP2002510386A | 2002-04-02 | |||
| JP2003515169A | 2003-04-22 | |||
| JP2005508323A | 2005-03-31 |
Other References:
ZHONG XIAOCUI, RAN RUI, GAO SHANHU, SHI MANLIN, SHI XIAN, LONG FEI, ZHOU YANQIU, YANG YANG, TANG XIANGLAN, LIN ANPING, HE WUYANG, : "Complex metabolic interactions between ovary, plasma, urine, and hair in ovarian cancer", FRONTIERS IN ONCOLOGY, FRONTIERS RESEARCH FOUNDATION, CH, vol. 12, 2 August 2022 (2022-08-02), CH , XP093137343, ISSN: 2234-943X, DOI: 10.3389/fonc.2022.916375
ZHANG LILI; HAN LEI; HE JUAN; LV JING; PAN RONGFANG; LV TENG: "A high serum-free fatty acid level is associated with cancer", JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, SPRINGER INTERNATIONAL, BERLIN., DE, vol. 146, no. 3, 26 November 2019 (2019-11-26), DE , pages 705 - 710, XP037039103, ISSN: 0171-5216, DOI: 10.1007/s00432-019-03095-8
ZHANG LILI; HAN LEI; HE JUAN; LV JING; PAN RONGFANG; LV TENG: "A high serum-free fatty acid level is associated with cancer", JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, SPRINGER INTERNATIONAL, BERLIN., DE, vol. 146, no. 3, 26 November 2019 (2019-11-26), DE , pages 705 - 710, XP037039103, ISSN: 0171-5216, DOI: 10.1007/s00432-019-03095-8
Attorney, Agent or Firm:
NISHIZAWA Kazuyoshi et al. (JP)
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