Title:
SARCOPENIC OBESITY INHIBITING COMPOSITION, AND PROPHYLACTIC AND/OR THERAPEUTIC COMPOSITION CONTAINING THE SAME FOR IMPROVING SARCOPENIC OBESITY INDUCED BY DIABETES
Document Type and Number:
WIPO Patent Application WO/2023/063033
Kind Code:
A1
Abstract:
[Problem] To provide a novel sarcopenic obesity inhibiting composition, and a prophylactic and/or therapeutic composition containing the same for improving sarcopenic obesity induced by diabetes. [Solution] A sarcopenic obesity inhibiting composition containing (A) guar gum degradation products having an average molecular weight of 1.7×103 to 2.9×105, at least 70 mass% thereof being within this range, and (B) a guar bean protein, the viscosity of a 1 mass% aqueous solution of the composition being less than or equal to 50 mPa・s as measured at 25°C and 60 rpm using a B-type viscometer, wherein the guar gum degradation products are contained in guar-derived endosperm and obtained by using microbe-derived β-mannanase to hydrolyze and reduce the molecular weight of galactomannan polysaccharide that has a galactose to mannose content ratio (galactose:mannose) in the range 1:1.5 to 1:2.1, the dietary fiber content, defined by the enzymatic-HPLC method, is at least 70 mass%, the content of oligosaccharides in the guar gum degradation products 15 mass% or less, among the amino acid compositions in the contained proteins, (glutamic acid + glutamine + aspartic acid + asparagine) ≥ 100 mg/100g, (cystine + tyrosine + serine + threonine) ≥ 40mg/100g, and all amino acids ≥ 150mg/100g, and the ratio (A)/(B) is 1000 or less.
Inventors:
HAMAGUCHI MASAHIDE (JP)
OKAMURA TAKURO (JP)
MIURA KATSURA (JP)
NAITO YUJI (JP)
FUKUI MICHIAKI (JP)
ABE AYA (JP)
OZEKI MAKOTO (JP)
OKAMURA TAKURO (JP)
MIURA KATSURA (JP)
NAITO YUJI (JP)
FUKUI MICHIAKI (JP)
ABE AYA (JP)
OZEKI MAKOTO (JP)
Application Number:
PCT/JP2022/035034
Publication Date:
April 20, 2023
Filing Date:
September 20, 2022
Export Citation:
Assignee:
TAIYOKAGAKU CO LTD (JP)
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
International Classes:
A23K10/30; A61K36/48; A23L33/125; A23L33/17; A61P3/04; A61P21/00
Domestic Patent References:
| WO2004110174A1 | 2004-12-23 |
Foreign References:
| JP2012162482A | 2012-08-30 | |||
| JP2012162483A | 2012-08-30 | |||
| JP2009072077A | 2009-04-09 | |||
| JP2022111399A | 2022-08-01 |
Other References:
SAKAKIDA, TOMOKI ET AL.: "Potential treatment for cancer sarcopenia targeting the Gu-muscle axis", JOURNAL OF JAPANESE SOCIETY OF GASTROENTEROLOGY, vol. 118, no. Suppl., 20 March 2021 (2021-03-20), pages A163, XP009545463, ISSN: 1349-7693
KOHARA, KATSUHIKO: "Sarcopenic Obesity", NIHON RONEN IGAKKAI ZASSHI - JAPANESE JOURNAL OF GERIATRICS, NIHON RONEN IGAKKAI, TOKYO, JP, vol. 51, no. 2, 30 November 2013 (2013-11-30), JP , pages 99 - 108, XP009547684, ISSN: 0300-9173
KOHARA, KATSUHIKO: "Sarcopenic Obesity", NIHON RONEN IGAKKAI ZASSHI - JAPANESE JOURNAL OF GERIATRICS, NIHON RONEN IGAKKAI, TOKYO, JP, vol. 51, no. 2, 30 November 2013 (2013-11-30), JP , pages 99 - 108, XP009547684, ISSN: 0300-9173
Attorney, Agent or Firm:
KOBAYASHI, Youhei (JP)
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