Title:
SARS-COV-2 VACCINE FOR THE PREVENTION AND TREATMENT OF CORONAVIRUS DISEASE (COVID-19)
Document Type and Number:
WIPO Patent Application WO/2023/154781
Kind Code:
A3
Abstract:
In December 2019, a zoonotic coronavirus crossed species to infect human populations for the third time in recent decades. The disease caused by the virus, SARS-CoV-2, has been officially named by the World Health Organization (WHO) as "COVID-19" for Coronavirus Disease, 2019, as the illness was first detected at the end of 2019. There is an urgent need for the development of vaccines to prevent non-infected individuals from contracting SARS-CoV-2, as well as to reduce the severity of COVID-19 disease. The invention provides methods of preventing or treating coronavirus disease (COVID-19) using immunogenic compositions described herein.
Inventors:
GUIRAKHOO FARSHAD (US)
Application Number:
PCT/US2023/062262
Publication Date:
October 26, 2023
Filing Date:
February 09, 2023
Export Citation:
Assignee:
VAXXINITY INC (US)
International Classes:
A61K39/215; A61K39/39; A61P11/00; A61P37/04; C07K14/165; C12N15/86
Domestic Patent References:
| WO2021168305A1 | 2021-08-26 | |||
| WO2021245611A1 | 2021-12-09 |
Other References:
TENFORDE MARK W., PATEL MANISH M., GAGLANI MANJUSHA, GINDE ADIT A., DOUIN DAVID J., TALBOT H. KEIPP, CASEY JONATHAN D., MOHR NICHO: "Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization Among Immunocompetent and Immunocompromised Adults — United States, August–December 2021", MORBIDITY AND MORTALITY WEEKLY REPORT., ATLANTA, GA., vol. 71, no. 4, 28 January 2022 (2022-01-28), pages 118 - 124, XP093103757, ISSN: 0149-2195, DOI: 10.15585/mmwr.mm7104a2
MOSS DANIEL L., RAPPAPORT JAY: "SARS-CoV-2 beta variant substitutions alter spike glycoprotein receptor binding domain structure and stability", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 297, no. 6, 1 December 2021 (2021-12-01), US , pages 101371, XP093103758, ISSN: 0021-9258, DOI: 10.1016/j.jbc.2021.101371
FORMICA NEIL, MALLORY RABURN, ALBERT GARY, ROBINSON MICHELLE, PLESTED JOYCE S., CHO IKSUNG, ROBERTSON ANDREANA, DUBOVSKY FILIP, GL: "Evaluation of a SARS-CoV-2 Vaccine NVX-CoV2373 in Younger and Older Adults", MEDRXIV, 1 March 2021 (2021-03-01), XP093103759, Retrieved from the Internet [retrieved on 20231121], DOI: 10.1101/2021.02.26.21252482
FALSEY ANN R., SOBIESZCZYK MAGDALENA E., HIRSCH IAN, SPROULE STEPHANIE, ROBB MERLIN L., COREY LAWRENCE, NEUZIL KATHLEEN M., HAHN W: "Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine", THE NEW ENGLAND JOURNAL OF MEDICINE, MASSACHUSETTS MEDICAL SOCIETY, US, vol. 385, no. 25, 16 December 2021 (2021-12-16), US , pages 2348 - 2360, XP093103760, ISSN: 0028-4793, DOI: 10.1056/NEJMoa2105290
RANZANI OTAVIO T, HITCHINGS MATT D T, DORION MURILO, D’AGOSTINI TATIANA LANG, DE PAULA REGIANE CARDOSO, DE PAULA OLIVIA FERREIRA P: "Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study", BMJ, pages n2015, XP093103761, DOI: 10.1136/bmj.n2015
ANONYMOUS: "AUSTRALIAN PRODUCT INFORMATION -COMIRNATY ™ (tozinameran) COVID-19 VACCINE [Tris/Sucrose Presentation] ", AUSTRALIAN PRODUCT INFORMATION, 1 December 2021 (2021-12-01), XP093103763, Retrieved from the Internet [retrieved on 20231121]
MOSS DANIEL L., RAPPAPORT JAY: "SARS-CoV-2 beta variant substitutions alter spike glycoprotein receptor binding domain structure and stability", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 297, no. 6, 1 December 2021 (2021-12-01), US , pages 101371, XP093103758, ISSN: 0021-9258, DOI: 10.1016/j.jbc.2021.101371
FORMICA NEIL, MALLORY RABURN, ALBERT GARY, ROBINSON MICHELLE, PLESTED JOYCE S., CHO IKSUNG, ROBERTSON ANDREANA, DUBOVSKY FILIP, GL: "Evaluation of a SARS-CoV-2 Vaccine NVX-CoV2373 in Younger and Older Adults", MEDRXIV, 1 March 2021 (2021-03-01), XP093103759, Retrieved from the Internet
FALSEY ANN R., SOBIESZCZYK MAGDALENA E., HIRSCH IAN, SPROULE STEPHANIE, ROBB MERLIN L., COREY LAWRENCE, NEUZIL KATHLEEN M., HAHN W: "Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine", THE NEW ENGLAND JOURNAL OF MEDICINE, MASSACHUSETTS MEDICAL SOCIETY, US, vol. 385, no. 25, 16 December 2021 (2021-12-16), US , pages 2348 - 2360, XP093103760, ISSN: 0028-4793, DOI: 10.1056/NEJMoa2105290
RANZANI OTAVIO T, HITCHINGS MATT D T, DORION MURILO, D’AGOSTINI TATIANA LANG, DE PAULA REGIANE CARDOSO, DE PAULA OLIVIA FERREIRA P: "Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study", BMJ, pages n2015, XP093103761, DOI: 10.1136/bmj.n2015
ANONYMOUS: "AUSTRALIAN PRODUCT INFORMATION -COMIRNATY ™ (tozinameran) COVID-19 VACCINE [Tris/Sucrose Presentation] ", AUSTRALIAN PRODUCT INFORMATION, 1 December 2021 (2021-12-01), XP093103763, Retrieved from the Internet
Attorney, Agent or Firm:
MICHAUD, Susan M. et al. (US)
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