Title:
SATURATED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PHARMACEUTICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/067566
Kind Code:
A1
Abstract:
Provided are a following compound (I), or a pharmaceutically acceptable salt, an ester, an optical isomer, a tautomer, a stereoisomer, a polymorph, a solvate, an N-oxide, an isotope-labeled compound, a metabolite, a chelate, a complex, a clathrate or a prodrug thereof, and a pharmaceutical composition containing the compound, and further provided are use of the compound as a 2α-type hypoxia-inducible factor (HIF-2α) inhibitor, use of the compound in the preparation of a medicament for a disease related to a 2α-type hypoxia-inducible factor, and a corresponding pharmaceutical composition.
Inventors:
LIU ZHIGUO (CN)
WU JIE (CN)
YE YANGLIANG (CN)
WANG HAO (CN)
WU JIE (CN)
YE YANGLIANG (CN)
WANG HAO (CN)
Application Number:
PCT/CN2023/121492
Publication Date:
April 04, 2024
Filing Date:
September 26, 2023
Export Citation:
Assignee:
SUZHOU ALPHAMA BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07D209/54; A61K31/4015; A61K31/4412; A61K31/4439; A61P35/00
Attorney, Agent or Firm:
FIWIS INTELLECTUAL PROPERTY LAW FIRM (CN)
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