Title:
SELF-ASSEMBLED MUSCLE-POWERED MICRODEVICES
Document Type and Number:
WIPO Patent Application WO2004014212
Kind Code:
A3
Abstract:
Cultured muscle tissue used as actuators in microelectromechanical systems (MEMS) for mechanical and electrical power generation can either be dissected or cultured from myoblasts and grown in situ. The MEMS is fabricated using conventional techniques (surface or bulk micromachining) and incorporating surface modification techniques and/or anchor structures to favor muscle attachment followed by post-processing to assemble dissected muscle tissue or grow the self-assembling muscle tissue at the desired sites. Initial post processing is done to incorporate PZT devices for energy conversion. Additional post-processing is then done for muscle tissue self-assembling; that includes coating the MEMS with polymers that will either repel or favor the muscle growth, and the culturing on the muscle tissue starting from myoblasts. The system is fueled by adding glucose to the medium in which it is contained.
Inventors:
MONTEMAGNO CARLO D
NEVES HERCULES P
NEVES HERCULES P
Application Number:
PCT/US2003/022497
Publication Date:
December 02, 2004
Filing Date:
August 07, 2003
Export Citation:
Assignee:
MT TECHNOLOGIES INC (US)
International Classes:
C12M1/34; C12N5/00; C12N5/077; C12Q1/00; A61B; (IPC1-7): C12N5/00
Foreign References:
| US5871511A | 1999-02-16 |
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