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Title:
SEPARATION METHOD, DETECTION METHOD, SIGNAL MEASUREMENT METHOD, METHOD FOR DETERMINING DISEASE, METHOD FOR EVALUATING DRUG EFFICACY OF DISEASE TREATMENT DRUG, KIT, AND LIQUID COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2015/068772
Kind Code:
A1
Abstract:
　The purpose of the present invention is to provide a method for separating a vesicle having a lipid bilayer membrane, the method having excellent efficiency of impurity removal, and the method not being prone to rupture a vesicle having a lipid bilayer membrane. A method for separating a vesicle having a lipid bilayer membrane, the method characterized by including a complex-forming step for bringing a biological sample including a vesicle having a lipid bilayer membrane into contact with a solid-phase carrier to which is bound a ligand for recognizing a surface antigen present on a surface of the vesicle and forming a complex of the vesicle and the solid-phase carrier, and a washing step for washing the complex, at least the complex-forming step or the washing step being performed in the presence of a nonionic surfactant.

Inventors:
FUJII HIROYA (JP)
MIZUUCHI MOTOAKI (JP)
YAMAGUCHI TETSUJI (JP)
ABE HIROKI (JP)
Application Number:
PCT/JP2014/079477
Publication Date:
May 14, 2015
Filing Date:
November 06, 2014
Export Citation:
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Assignee:
JSR CORP (JP)
JSR LIFE SCIENCES CORP (JP)
International Classes:
G01N33/544; G01N33/50; G01N33/53; G01N33/543
Domestic Patent References:
WO2013022995A22013-02-14
WO2010065968A12010-06-10
Foreign References:
JP2011510309A2011-03-31
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
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