SERINE DERIVATIVE - YAMANOUCHI PHARMA CO LTD

Title:

SERINE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/1994/025450

Kind Code:

A1

Abstract:

A serine derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, having an anti-PCP(phencyclidine) activity and being useful as a psychotropic, wherein X represents sulfur or oxygen; Y represents nitrogen or CH; R1 and R2 represent each independently hydrogen, lower alkyl or an amino-protecting group, or R1 and R2 may be combined together to form 4- to 9-membered nitrogenous cycloalkyl; R3 represents hydrogen, carboxy, protected carboxy, aralkyl, or lower alkyl which may be hydroxylated; R4 represents hydrogen or hydroxy; R5 represents hydrogen or lower alkyl; A represents lower alkylene; B represents (1) an (un)saturated 4- to 10-membered nitrogenous cycloalkyl group which may be substituted by lower alkyl or aralkyl, or (2) a bicyclic nitrogenous hydrocarbon ring group comprising a 4- to 8-membered nitrogenous cycloalkyl group and a benzene ring fused together; and ._._._ represents a single or a double bond.

More Like This:

JP2009035666	MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT
WO/2003/059064	INSECTICIDES CONTAINING HYDRAZONE DERIVATIVES AS THE ACTIVE INGREDIENT AND NOVEL HYDRAZONE DERIVATIVES
JP2000500469	[Title of the Invention] A benzamide oxime-based prodrug as an anti-pneumocystis agent

Inventors:

NODA ICHIO (JP)
IWATA MASAHIRO (JP)
SAKAMOTO SHUICHI (JP)
KOSHIYA KAZUO (JP)
MORITA TAKUMA (JP)
KOHARA ATSUYUKI (JP)

Application Number:

PCT/JP1994/000697

Publication Date:

November 10, 1994

Filing Date:

April 26, 1994

Export Citation:

Click for automatic bibliography generation Help

Assignee:

YAMANOUCHI PHARMA CO LTD (JP)
NODA ICHIO (JP)
IWATA MASAHIRO (JP)
SAKAMOTO SHUICHI (JP)
KOSHIYA KAZUO (JP)
MORITA TAKUMA (JP)
KOHARA ATSUYUKI (JP)

International Classes:

C07D307/52; C07D307/54; C07D333/20; C07D333/24; C07D409/06; (IPC1-7): C07D307/52; C07D333/20; C07D333/24; C07D409/06; C07D413/06; C07D407/06; A61K31/34; A61K31/40; A61K31/445; A61K31/55

Foreign References:

JPH05262759A

1993-10-12

Other References: