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Title:
SERPIN PEPTIDES AND METHODS OF USING THE SAME
Document Type and Number:
WIPO Patent Application WO/2023/133078
Kind Code:
A3
Abstract:
Disclosed herein are SERPIN peptides, and analogues and derivatives thereof, and uses of the same for treating various conditions associated with LRP1 or TSLP.

Inventors:
AUSTIN DANA (US)
GELBER COHAVA (US)
Application Number:
PCT/US2022/082669
Publication Date:
August 17, 2023
Filing Date:
December 30, 2022
Export Citation:
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Assignee:
SERPIN PHARMA LLC (US)
International Classes:
A61K38/55; A61P9/10; A61P17/02; C07K14/81; A61K31/688; A61K47/60
Domestic Patent References:
WO2017040287A12017-03-09
WO2021092050A12021-05-14
Foreign References:
US20210145974A12021-05-20
US20190000799A12019-01-03
Other References:
BOITANO SCOTT, FLYNN ANDREA N., SHERWOOD CARA L., SCHULZ STEPHANIE M., HOFFMAN JUSTIN, GRUZINOVA IRINA, DAINES MICHAEL O.: "Alternaria alternata serine proteases induce lung inflammation and airway epithelial cell activation via PAR 2", AMERICAN JOURNAL OF PHYSIOLOGY - LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, AMERICAN PHYSIOLOGICAL SOCIETY, US, vol. 300, no. 4, 1 April 2011 (2011-04-01), US , pages 605 - 614, XP093085422, ISSN: 1040-0605, DOI: 10.1152/ajplung.00359.2010
Attorney, Agent or Firm:
WISE, Michael J. et al. (US)
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