Title:
SHEET-LIKE HEMOSTATIC MATERIAL EMPLOYING POLY-γ-GLUTAMIC ACID, AND METHOD OF MANUFACTURING SAME
Document Type and Number:
WIPO Patent Application WO/2017/183640
Kind Code:
A1
Abstract:
A sheet-like hemostatic material (10A to 10E) is provided with: an adhesive layer (11) which is a sheet formed from at least poly-γ-glutamic acid (γ-PGA) and which serves as a surface for affixing to a bleeding site; and a covering layer (12) which is a sheet formed from at least one biodegradable material (covering material) other than γ-PGA, and which serves as the opposite surface to the affixing surface. At least one of the adhesive layer (11) and the covering layer (12) is a single sheet. If the adhesive layer (11) is a single sheet, the adhesive layer (11) should be a sponge-like sheet, and if the adhesive layer (11) is a partial layer, the adhesive layer (11) should be a sponge-like sheet or a nonporous layer. Alternatively, in another sheet-like hemostatic material, a sheet which is formed from at least poly-γ-glutamic acid (γ-PGA) and to which at least one of a saccharide and collagen has been added is provided as the adhesive layer.
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Inventors:
NAKAMURA YUSUKE
SUGAWARA YOSHIKATSU
MATSUDA KAZUHISA
SUGAWARA YOSHIKATSU
MATSUDA KAZUHISA
Application Number:
PCT/JP2017/015604
Publication Date:
October 26, 2017
Filing Date:
April 18, 2017
Export Citation:
Assignee:
NIPRO CORP (JP)
International Classes:
A61L15/26; A61L15/28; A61L15/32; A61L15/56
Foreign References:
| JP2005046228A | 2005-02-24 | |||
| JP2013013743A | 2013-01-24 | |||
| JP2015139603A | 2015-08-03 | |||
| JP2009089837A | 2009-04-30 | |||
| US20130296459A1 | 2013-11-07 |
Other References:
HUANG,MEI-HUA ET AL.: "Swelling and biocompatibility of sodium alginate/poly(y- glutamic acid) hydrogels", POLYMERS FOR ADVANCED TECHNOLOGIES, vol. 21, no. 8, 2010, pages 561 - 567, XP055433265
HSU, FU-YIN ET AL.: "Fabrication and evaluation of a biodegradable cohesive plug based on recostituted collagen/y-polyglutamic acid", J BIOMED MATER RES PT B APPL BIOMATER, vol. 95, no. 1, 2010, pages 29 - 35, XP055580877
See also references of EP 3446719A4
HSU, FU-YIN ET AL.: "Fabrication and evaluation of a biodegradable cohesive plug based on recostituted collagen/y-polyglutamic acid", J BIOMED MATER RES PT B APPL BIOMATER, vol. 95, no. 1, 2010, pages 29 - 35, XP055580877
See also references of EP 3446719A4
Attorney, Agent or Firm:
PATENT CORPORATE BODY ARCO PATENT OFFICE (JP)
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