Title:
SINGLE MOLECULE IMAGING TECHNIQUES TO AID CRYSTALLIZATION
Document Type and Number:
WIPO Patent Application WO/2012/142541
Kind Code:
A8
Abstract:
This invention relates to a method to rapidly find crystallization conditions for a biomolecule in a desired conformation using single-molecule, fluorescent resonance energy transfer (smFRET) imaging techniques. The method provides significant cost and time advantages over the empricial exploration for crystallization conditions.
Inventors:
BLANCHARD SCOTT C (US)
FELDMAN MICHAEL BRIAN (US)
WANG LEYI (US)
ALTMAN ROGER (US)
FELDMAN MICHAEL BRIAN (US)
WANG LEYI (US)
ALTMAN ROGER (US)
Application Number:
PCT/US2012/033698
Publication Date:
August 22, 2013
Filing Date:
April 14, 2012
Export Citation:
Assignee:
UNIV CORNELL (US)
BLANCHARD SCOTT C (US)
FELDMAN MICHAEL BRIAN (US)
WANG LEYI (US)
ALTMAN ROGER (US)
BLANCHARD SCOTT C (US)
FELDMAN MICHAEL BRIAN (US)
WANG LEYI (US)
ALTMAN ROGER (US)
International Classes:
G01N33/52; G01N33/50
Attorney, Agent or Firm:
GROLZ, Edward W. (Scott Murphy & Presser,400 Garden City Plaza,Suite 30, Garden City New York, US)
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