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Title:
SLIPPERY LIQUID-INFUSED POROUS SURFACES AND BIOLOGICAL APPLICATIONS THEREOF
Document Type and Number:
WIPO Patent Application WO/2012/100100
Kind Code:
A3
Abstract:
A self-healing, scratch resistant slippery surface that is manufactured by wicking a chemically-inert, high-density liquid coating over a roughened solid surface featuring micro and nanoscale topographies is described. Such a slippery surface shows anti-wetting properties, as well as exhibits significant reduction of adhesion of a broad range of biological materials, including particles in suspension or solution. Specifically, the slippery surfaces can be applied to medical devices and equipment to effectively repel biological materials such as blood, and prevent, reduce, or delay coagulation and surface-mediated clot formation. Moreover, the slippery surfaces can be used to prevent fouling by microorganisms such as bacteria.

Inventors:
AIZENBERG JOANNA (US)
HATTON BENJAMIN (US)
INGBER DONALD ELLIOTT (US)
SUPER MICHAEL (US)
WONG TAK SING (US)
Application Number:
PCT/US2012/021929
Publication Date:
October 18, 2012
Filing Date:
January 19, 2012
Export Citation:
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Assignee:
HARVARD COLLEGE (US)
AIZENBERG JOANNA (US)
HATTON BENJAMIN (US)
INGBER DONALD ELLIOTT (US)
SUPER MICHAEL (US)
WONG TAK SING (US)
International Classes:
C09D5/16; A61L15/24; A61L15/34; A61L15/42; A61L15/46; A61L27/28; A61L27/34; A61L27/50; A61L33/00; A61L33/06; B01L3/00
Domestic Patent References:
WO1999036490A11999-07-22
WO2006091235A12006-08-31
WO1993017077A11993-09-02
Foreign References:
JP2004037764A2004-02-05
JPH05240251A1993-09-17
JPH01170932A1989-07-06
US5624713A1997-04-29
DE19818956A11998-11-26
Other References:
HOLGER F. BOHN ET AL: "Insect aquaplaning: Nepenthes pitcher plants capture prey with the peristome, a fully wettable water-lubricated anisotropic surface", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, 21 September 2008 (2008-09-21), pages 14138 - 14143, XP055025182, Retrieved from the Internet [retrieved on 20120420], DOI: 10.1073/pnas.0405885101
ULRIKE BAUER ET AL: "The insect-trapping rim of Nepenthes pitchers: surface structure and function", PLANT SIGNALING & BEHAVIOR, vol. 4, no. 11, 1 November 2009 (2009-11-01), pages 1019 - 1023, XP055025454, ISSN: 1559-2316, DOI: 10.4161/psb.4.11.9664
ROBERT N. WENZEL: "RESISTANCE OF SOLID SURFACES TO WETTING BY WATER", INDUSTRIAL & ENGINEERING CHEMISTRY, vol. 28, no. 8, 1 August 1936 (1936-08-01), pages 988 - 994, XP055025240, ISSN: 0019-7866, DOI: 10.1021/ie50320a024
CASSIE A B D ET AL: "Wettability of porous surfaces", TRANSACTIONS OF THE FARADAY SOCIETY, BUTTERWORTHS SCIENTIFIC PUBLICATIONS LTD, LONDON, GB, vol. 40, 1 January 1944 (1944-01-01), pages 546 - 551, XP008120964, ISSN: 0014-7672, DOI: 10.1039/TF9444000546
VAHID HEJAZI ET AL: "Wetting Transitions in Two-, Three-, and Four-Phase Systems", LANGMUIR, vol. 28, no. 4, 31 January 2012 (2012-01-31), pages 2173 - 2180, XP055025134, ISSN: 0743-7463, DOI: 10.1021/la2038284
TAK-SING WONG ET AL: "Bioinspired self-repairing slippery surfaces with pressure-stable omniphobicity", NATURE, vol. 477, no. 7365, 1 January 2011 (2011-01-01), pages 443 - 447, XP055025132, ISSN: 0028-0836, DOI: 10.1038/nature10447
Attorney, Agent or Firm:
SCOZZAFAVA, Mary Rose et al. (60 State StreetBoston, MA, US)
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