SMALL MOLECULE IL-17A MODULATORS

Title:

SMALL MOLECULE IL-17A MODULATORS

Document Type and Number:

WIPO Patent Application WO/2023/202664

Kind Code:

A1

Abstract:

Disclosed herein are fused bi-cyclic compounds used as Small Molecule IL-17A Modulators. Disclosed herein is the use of these Small Molecule IL-17A Modulators for the use of decreasing IL-17 activity by inhibition, and the use of such compounds for the use in the treatment of autoimmune diseases or inflammatory diseases.

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Inventors:

XUE HAI (CN)
GUO YUNHANG (CN)
CHEN SI (CN)
WANG ZHIWEI (CN)

Application Number:

PCT/CN2023/089491

Publication Date:

October 26, 2023

Filing Date:

April 20, 2023

Export Citation:

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Assignee:

BEIGENE LTD (GB)
XUE HAI (CN)

International Classes:

C07D403/12; A61K31/415; A61K31/422; A61P29/00; A61P37/00; C07D407/14; C07D409/14; C07D413/12; C07D413/14

Domestic Patent References:

WO2020011731A1	2020-01-16
WO2020182666A1	2020-09-17

Foreign References:

CN110769821A	2020-02-07
CN110511213A	2019-11-29
CN112824398A	2021-05-21
CN113316451A	2021-08-27

Attorney, Agent or Firm:

WU, FENG & ZHANG (CN)

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