Title:
SOLID FORMULATION HAVING EXCELLENT STABILITY
Document Type and Number:
WIPO Patent Application WO/2019/208540
Kind Code:
A1
Abstract:
Provided is a solid formulation containing a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, a stabilizer, a sugar alcohol and/or a saccharide, a water-soluble polymer, and an inorganic material, and the solid formulation exhibits a good stability, water suspendability, and flowability.
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Inventors:
MIZUTANI NAOYA (JP)
MORIMOTO MASAYUKI (JP)
YAMASHITA MAKI (JP)
ITO MASAAKI (JP)
KIMURA GO (JP)
MORIMOTO MASAYUKI (JP)
YAMASHITA MAKI (JP)
ITO MASAAKI (JP)
KIMURA GO (JP)
Application Number:
PCT/JP2019/017146
Publication Date:
October 31, 2019
Filing Date:
April 23, 2019
Export Citation:
Assignee:
SHIONOGI & CO (JP)
International Classes:
A61K31/53; A61K9/20; A61K47/02; A61K47/04; A61K47/14; A61K47/22; A61K47/26; A61K47/38; A61P31/16
Domestic Patent References:
WO2016175224A1 | 2016-11-03 | |||
WO2009044854A1 | 2009-04-09 | |||
WO2019098259A1 | 2019-05-23 | |||
WO2016175224A1 | 2016-11-03 |
Foreign References:
JP2001512433A | 2001-08-21 | |||
JPH09249563A | 1997-09-22 | |||
JP2013523757A | 2013-06-17 | |||
JP2000034227A | 2000-02-02 | |||
JP2009536940A | 2009-10-22 | |||
JP2007269783A | 2007-10-18 | |||
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JP2008007420A | 2008-01-17 | |||
JP2016079102A | 2016-05-16 | |||
JP2001512433A | 2001-08-21 | |||
JP2014534215A | 2014-12-18 |
Other References:
YOUNG-A HEO: "Baloxavir: First Global Approval", DRUGS, vol. 78, no. 6, 5 April 2018 (2018-04-05), pages 693 - 697, XP055741172, ISSN: 0012-6667, DOI: 10.1007/s40265-018-0899-1
Attorney, Agent or Firm:
SUGITA Ken-ichi et al. (JP)
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