Title:
SOLID PREPARATION AND MANUFACTURING METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/206159
Kind Code:
A1
Abstract:
The present invention relates to a solid preparation that contains 2-{4-[N-(5,6-diphenyl pyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide (generic name "selexipag"), and a manufacturing method thereof. This solid preparation contains (A) selexipag, (B) starch, and (C) a granulated substance containing at least one type of binder selected from the group consisting of hydroxypropyl cellulose and hypromellose, wherein the content ratio of component (B) per 100 parts by mass of the granulated substance is at least 20 parts by mass (but excluding 30.2-30.4 parts by mass), and the content ratio of component (C) per 100 parts by mass of the granulated substance is at most 4 parts by mass.
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Inventors:
YAMADA RIE (JP)
OMAGARI HAZUKI (JP)
TANAKA TOSHINORI (JP)
OMAGARI HAZUKI (JP)
TANAKA TOSHINORI (JP)
Application Number:
PCT/JP2021/014987
Publication Date:
October 14, 2021
Filing Date:
April 09, 2021
Export Citation:
Assignee:
NIPPON SHINYAKU CO LTD (JP)
International Classes:
A61K31/4965; A61K9/20; A61K9/28; A61K47/26; A61K47/36; A61K47/38; A61P3/10; A61P9/00; A61P11/00; A61P11/06; A61P13/12; A61P17/00
Domestic Patent References:
| WO2017098998A1 | 2017-06-15 | |||
| WO2019163822A1 | 2019-08-29 | |||
| WO2019098300A1 | 2019-05-23 |
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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