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Title:
SPERM MOTILITY IMPROVING AGENT AND SPERM MOTILITY IMPROVING METHOD
Document Type and Number:
WIPO Patent Application WO/2022/054778
Kind Code:
A1
Abstract:
[Problem] To provide a sperm motility improving agent that is highly safe and that can effectively improve sperm motility. [Solution] A sperm motility improving agent containing a nicotinamide mononucleotide as an active ingredient.

Inventors:
TANAKA MEGUMI (JP)
TANAKA TSUNEMARU (JP)
SHIMADA MASAYUKI (JP)
Application Number:
PCT/JP2021/032772
Publication Date:
March 17, 2022
Filing Date:
September 07, 2021
Export Citation:
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Assignee:
MIRAILAB BIOSCIENCE INC (JP)
UNIV HIROSHIMA (JP)
International Classes:
A61K31/706; A23L2/52; A23L33/13; A61K31/475; A61P15/00; A61P43/00
Domestic Patent References:
WO2020013086A12020-01-16
WO2020115764A12020-06-11
WO2018200357A12018-11-01
WO2015064109A12015-05-07
Foreign References:
JP2014520526A2014-08-25
JP2005053783A2005-03-03
Other References:
YOUNGSON NEIL A, UDDIN G MEZBAH, DAS ABHIRUP, MARTINEZ CARL, CONNAUGHTON HALEY S, WHITING SARA, YU JOSEPHINE, SINCLAIR DAVID A, AI: "Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice", JOURNALS OF REPRODUCTION & FERTILITY, BIOSCIENTIFICA LTD., GB, vol. 158, no. 2, 1 August 2019 (2019-08-01), GB , pages 171 - 181, XP055909983, ISSN: 1470-1626, DOI: 10.1530/REP-18-0574
GRANDHAYE JÉRÉMY, PARTYKA AGNIESZKA, LIGOCKA ZUZANNA, DUDEK AGATA, NIŻAŃSKI WOJCIECH, JEANPIERRE ERIC, ESTIENNE ANTHONY, FROMENT P: "Metformin Improves Quality of Post-Thaw Canine Semen", ANIMALS, vol. 10, no. 2, 12 February 2020 (2020-02-12), XP055909985, DOI: 10.3390/ani10020287
BIOORG. MED. CHEM. LETT., vol. 12, 2002, pages 1135 - 1137
CHEM. COMM., 1999, pages 729 - 730
Attorney, Agent or Firm:
SHIMAZAKI Eiichiro (JP)
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