SPIRO (3,3'-PHENYLPYRROLIDINE OXYINDOLE) LIVER X RECEPTOR MODULATOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Title:

SPIRO (3,3'-PHENYLPYRROLIDINE OXYINDOLE) LIVER X RECEPTOR MODULATOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2021/008014

Kind Code:

A1

Abstract:

Disclosed are a spiro (3,3'-phenylpyrrolidine oxyindole) liver X receptor modulator, a preparation method and an application, the receptor modulator specifically being a compound represented by formula (I), or a stereoisomer, geometric isomer, tautomer, nitrogen oxide, hydrate, solvate, metabolite, pharmaceutically acceptable salt, or prodrug of the compound represented by formula (I).

More Like This:

WO/2010/054961	SPIRO-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENES
JP7346441	Substituted pyridines and pyrimidines and their use as GLUN2B receptor modulators
JP5139306	Tertiary α-aminocarboxamide derivative as a regulator of voltage-gated sodium channels

Inventors:

CHEN HAO (CN)
GU QIONG (CN)
CHEN ZIYANG (CN)
ZHANG ZIZHEN (CN)
XU JUN (CN)

Application Number:

PCT/CN2019/116017

Publication Date:

January 21, 2021

Filing Date:

November 06, 2019

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MW CANNABIS PHARMACEUTICAL INC (CN)

International Classes:

C07D487/10; A61K31/407; A61P3/00; A61P7/00; A61P9/10; A61P17/00; A61P19/02; A61P19/10; A61P25/16; A61P25/28; A61P35/00

Domestic Patent References:

WO2011101297A1	2011-08-25
WO2011101297A1	2011-08-25
WO2016100619A2	2016-06-23

Foreign References:

CN110305141A	2019-10-08
CN110330498A	2019-10-15

Other References:

WEISBACH, JERRY A. ET AL.: "Synthesis and pharmacology of some β-spiroindolenines and indolines", JOURNAL OF MEDICINAL CHEMISTRY, vol. 7, no. 6, 30 November 1964 (1964-11-30), XP055774065, ISSN: 0022-2623, DOI: 20200110163345A

Attorney, Agent or Firm:

TSINGYIHUA INTELLECTUAL PROPERTY LLC (CN)

Download PDF:

View/Download PDF PDF Help

Previous Patent: FOLDING FLEXIBLE SCREEN WEARABLE TERMINAL

Next Patent: INTENTION RECOGNITION METHOD, DEVICE AND COMPUTER READABLE STORAGE MEDIUM