STABILIZED EFINACONAZOLE-CONTAINING PHARMACEUTICAL COMPOSITION COMPRISING COMBINATION OF CHELATING AGENT AND ANTIOXIDANT

Title:

STABILIZED EFINACONAZOLE-CONTAINING PHARMACEUTICAL COMPOSITION COMPRISING COMBINATION OF CHELATING AGENT AND ANTIOXIDANT

Document Type and Number:

WIPO Patent Application WO/2021/054534

Kind Code:

A3

Abstract:

The present invention provides an efinaconazole-containing solution-type topically-administered pharmaceutical composition comprising: a combination of diethylene glycol monoethyl ether and isopropyl myristate as a nonvolatile solvent; and a specific combination of a chelating agent and an antioxidant. The pharmaceutical composition of the present invention has excellent physicochemical stability.

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Inventors:

KIM BEOM-JOON (KR)
KOO KYO-TAN (KR)

Application Number:

PCT/KR2019/017072

Publication Date:

May 14, 2021

Filing Date:

December 05, 2019

Export Citation:

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Assignee:

BIOBELIEF CO LTD (KR)

International Classes:

A61K9/08; A61K9/00; A61K31/454; A61K47/08; A61K47/12; A61K47/14; A61K47/18; A61P31/10

Domestic Patent References:

WO2018110693A1

2018-06-21

Foreign References:

KR20160068812A	2016-06-15
KR20140072016A	2014-06-12
KR20160087898A	2016-07-22
US20100317695A1	2010-12-16

Attorney, Agent or Firm:

OH, Kook-Jin (KR)

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