STABLE FORMULATIONS OF ANGIOTENSIN CONVERTING ENZYME (ACE) INHIBITORS

Title:

STABLE FORMULATIONS OF ANGIOTENSIN CONVERTING ENZYME (ACE) INHIBITORS

Document Type and Number:

WIPO Patent Application WO2003075842

Kind Code:

A3

Abstract:

A stable pharmaceutical composition comprising a) a therapeutically effective amount of an Angiotensin Converting Enzyme ("ACE") inhibitor which is susceptible to degradation or its salt; b) a greater than stoichiometric amount of an alkali or alkaline earth metal carbonate, relative to the amount of ACE inhibitor or its salt; and c) a pharmaceutically acceptable carrier, including a process for the manufacture of such compositions.

Inventors:

STOFIK SCOTT
GWOZDZ ROBERT
PELLONI CHRISTOPHER L
JAMES JOHN C

Application Number:

PCT/US2003/006606

Publication Date:

January 08, 2004

Filing Date:

March 06, 2003

Export Citation:

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Assignee:

TEVA PHARMECEUTICALS USA INC (US)

International Classes:

A61K9/20; A61K31/44; (IPC1-7): A61K31/44

Foreign References:

US5977159A

1999-11-02

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