Title:
STABLE PHARMACEUTICAL COMPOSITION COMPRISING CARBETOCIN AND SUITABLE FOR VAGINAL ADMINISTRATION, AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2018/113273
Kind Code:
A1
Abstract:
A pharmaceutical composition comprising carbetocin, comprising (percent by weight): 0.5%-7% of carbetocin, 1%-10% of a water-soluble matrix material, 0.5%-5% of an amino acid anionic surfactant, 0.1%-5% of a humectant, and the balance of water. The amino acid anionic surfactant in the pharmaceutical composition can effectively eliminate the clinical difference caused by the individual difference, can effectively and stably stimulate uterine contraction, and can maintain the stability of a drug.
Inventors:
ZHENG CHUN LIAN (CN)
TAO AN JIN (CN)
LING RU GUANG (CN)
LIN HAO WEN (CN)
YUAN JIAN CHENG (CN)
TAO AN JIN (CN)
LING RU GUANG (CN)
LIN HAO WEN (CN)
YUAN JIAN CHENG (CN)
Application Number:
PCT/CN2017/092718
Publication Date:
June 28, 2018
Filing Date:
July 13, 2017
Export Citation:
Assignee:
HYBIO PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K9/06; A61K38/095; A61K47/18; A61P7/04; A61P15/00
Foreign References:
| US6894026B1 | 2005-05-17 | |||
| CN102228678A | 2011-11-02 |
Attorney, Agent or Firm:
BEIJING CHENGHUI LAW FIRM (CN)
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