Title:
STING ANTAGONIST-FILLED UREASE-POWERED NANOMOTOR-BASED BLADDER CANCER IMMUNOTHERAPY AGENT
Document Type and Number:
WIPO Patent Application WO/2023/140717
Kind Code:
A1
Abstract:
The present invention relates to a chitosan-heparin nanomotor and a method for producing same. A STING antagonist-filled urease-based chitosan-heparin nanomotor delivers the STING antagonist directly to bladder mucosal cells in the bladder, and thus can induce an immune response.
Inventors:
CHOI HYUN SIK (KR)
JEONG SEUNG-HWAN (KR)
JEONG SEUNG-HWAN (KR)
Application Number:
PCT/KR2023/001103
Publication Date:
July 27, 2023
Filing Date:
January 25, 2023
Export Citation:
Assignee:
PHI BIOMED INC (KR)
International Classes:
A61K9/51; A61K45/06; A61P35/00
Foreign References:
| EP3663257A1 | 2020-06-10 | |||
| KR20160013342A | 2016-02-04 | |||
| KR20210114151A | 2021-09-23 | |||
| KR20140041438A | 2014-04-04 |
Other References:
HORTELÃO ANA C., CARRASCOSA RAFAEL, MURILLO-CREMAES NEREA, PATIÑO TANIA, SÁNCHEZ SAMUEL: "Targeting 3D Bladder Cancer Spheroids with Urease-Powered Nanomotors", ACS NANO, AMERICAN CHEMICAL SOCIETY, US, vol. 13, no. 1, 22 January 2019 (2019-01-22), US , pages 429 - 439, XP093078421, ISSN: 1936-0851, DOI: 10.1021/acsnano.8b06610
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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