Title:
STRAIN FOR DEGRADING DEOXYNIVALENOL AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/111287
Kind Code:
A1
Abstract:
The present invention relates to the fields of microorganisms, feed, food and ecological restoration, in particular to a strain for degrading deoxynivalenol (DON) and the use thereof. The strain has the deposit number CCTCC No. M 2020565. The strain can grow by means of taking the toxic compound DON as a sole carbon source, and convert the DON into chemical components for itself. The reaction process is irreversible, the reaction conditions are moderate, and secondary pollution cannot be caused. The strain provided in the present invention can be used for preparing a biological detoxification preparation for DON. The strain provided in the present invention can be used for degrading DON in feed and food raw materials, primary processing products, deep processing products and related processing byproducts. The strain provided in the present invention can be applied to various ecosystems such as soil or bodies of water polluted by DON to achieve the purposes of DON degradation and ecological restoration.
Inventors:
LUO HUIYING (CN)
ZHANG HONGHAI (CN)
YAO BIN (CN)
HUANG HUOQING (CN)
WANG YARU (CN)
BAI YINGGUO (CN)
SU XIAOYUN (CN)
WANG YUAN (CN)
TU TAO (CN)
ZHANG JIE (CN)
YU HUIMIN (CN)
QIN XING (CN)
WANG XIAOLU (CN)
ZHANG HONGHAI (CN)
YAO BIN (CN)
HUANG HUOQING (CN)
WANG YARU (CN)
BAI YINGGUO (CN)
SU XIAOYUN (CN)
WANG YUAN (CN)
TU TAO (CN)
ZHANG JIE (CN)
YU HUIMIN (CN)
QIN XING (CN)
WANG XIAOLU (CN)
Application Number:
PCT/CN2021/129928
Publication Date:
June 02, 2022
Filing Date:
November 11, 2021
Export Citation:
Assignee:
INST OF ANIMAL SCIENCE OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN)
International Classes:
C12N1/20; A23K10/12; A23L5/20; B09C1/10; C02F3/34; C02F101/34; C12R1/01
Foreign References:
| CN112126607A | 2020-12-25 | |||
| JP2008220184A | 2008-09-25 |
Other References:
ZHANG HONGHAI, ZHANG HENG, QIN XING, WANG XIAOLU, WANG YUAN, BIN YAO, XIE XIANGMING, ZHENG FEI, LUO HUIYING: "Biodegradation of Deoxynivalenol by Nocardioides sp. ZHH-013: 3-keto-Deoxynivalenol and 3-epi-Deoxynivalenol as Intermediate Products", FRONTIERS IN MICROBIOLOGY, vol. 12, 19 July 2021 (2021-07-19), pages 1 - 9, XP055934768, DOI: 10.3389/fmicb.2021.658421
MORIMURA HIROYUKI, UESAKA KAZUMA, ITO MICHIHIRO, YOSHIDA SHIGENOBU, KOITABASHI MOTOO, TSUSHIMA SEIYA, SATO IKUO: "Draft Genome Sequence of Deoxynivalenol-Degrading Actinomycete Nocardioides sp. Strain LS1, Isolated from Wheat Leaves in Japan", MICROBIOLOGY RESOURCE ANNOUNCEMENTS, vol. 8, no. 10, 7 March 2019 (2019-03-07), pages 1 - 2, XP055934771, DOI: 10.1128/MRA.01650-18
YOKO IKUNAGA; IKUO SATO; STEPHANIE GROND; NOBUTAKA NUMAZIRI; SHIGENOBU YOSHIDA; HIROKO YAMAYA; SYUNTARO HIRADATE; MORIFUMI HASEGAW: "sp. strain WSN05-2, isolated from a wheat field, degrades deoxynivalenol, producing the novel intermediate 3--deoxynivalenol", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 89, no. 2, 21 September 2010 (2010-09-21), Berlin, DE , pages 419 - 427, XP019870366, ISSN: 1432-0614, DOI: 10.1007/s00253-010-2857-z
SATO IKUO, ITO MICHIHIRO, ISHIZAKA MASUMI, IKUNAGA YOKO, SATO YUKARI, YOSHIDA SHIGENOBU, KOITABASHI MOTOO, TSUSHIMA SEIYA: "Thirteen novel deoxynivalenol-degrading bacteria are classified within two genera with distinct degradation mechanisms", FEMS MICROBIOLOGY LETTERS, NO LONGER PUBLISHED BY ELSEVIER, vol. 327, no. 2, 1 February 2012 (2012-02-01), pages 110 - 117, XP055934774, ISSN: 0378-1097, DOI: 10.1111/j.1574-6968.2011.02461.x
MORIMURA HIROYUKI, ITO MICHIHIRO, YOSHIDA SHIGENOBU, KOITABASHI MOTOO, TSUSHIMA SEIYA, CAMAGNA MAURIZIO, CHIBA SOTARO, TAKEMOTO DA: "In Vitro Assessment of Biocontrol Effects on Fusarium Head Blight and Deoxynivalenol (DON) Accumulation by DON-Degrading Bacteria", TOXINS, vol. 12, no. 399, pages 1 - 13, XP055934776, DOI: 10.3390/toxins12060399
MORIMURA HIROYUKI, UESAKA KAZUMA, ITO MICHIHIRO, YOSHIDA SHIGENOBU, KOITABASHI MOTOO, TSUSHIMA SEIYA, SATO IKUO: "Draft Genome Sequence of Deoxynivalenol-Degrading Actinomycete Nocardioides sp. Strain LS1, Isolated from Wheat Leaves in Japan", MICROBIOLOGY RESOURCE ANNOUNCEMENTS, vol. 8, no. 10, 7 March 2019 (2019-03-07), pages 1 - 2, XP055934771, DOI: 10.1128/MRA.01650-18
YOKO IKUNAGA; IKUO SATO; STEPHANIE GROND; NOBUTAKA NUMAZIRI; SHIGENOBU YOSHIDA; HIROKO YAMAYA; SYUNTARO HIRADATE; MORIFUMI HASEGAW: "sp. strain WSN05-2, isolated from a wheat field, degrades deoxynivalenol, producing the novel intermediate 3--deoxynivalenol", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 89, no. 2, 21 September 2010 (2010-09-21), Berlin, DE , pages 419 - 427, XP019870366, ISSN: 1432-0614, DOI: 10.1007/s00253-010-2857-z
SATO IKUO, ITO MICHIHIRO, ISHIZAKA MASUMI, IKUNAGA YOKO, SATO YUKARI, YOSHIDA SHIGENOBU, KOITABASHI MOTOO, TSUSHIMA SEIYA: "Thirteen novel deoxynivalenol-degrading bacteria are classified within two genera with distinct degradation mechanisms", FEMS MICROBIOLOGY LETTERS, NO LONGER PUBLISHED BY ELSEVIER, vol. 327, no. 2, 1 February 2012 (2012-02-01), pages 110 - 117, XP055934774, ISSN: 0378-1097, DOI: 10.1111/j.1574-6968.2011.02461.x
MORIMURA HIROYUKI, ITO MICHIHIRO, YOSHIDA SHIGENOBU, KOITABASHI MOTOO, TSUSHIMA SEIYA, CAMAGNA MAURIZIO, CHIBA SOTARO, TAKEMOTO DA: "In Vitro Assessment of Biocontrol Effects on Fusarium Head Blight and Deoxynivalenol (DON) Accumulation by DON-Degrading Bacteria", TOXINS, vol. 12, no. 399, pages 1 - 13, XP055934776, DOI: 10.3390/toxins12060399
Attorney, Agent or Firm:
FASIN IP & PARTNERS (CN)
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