Title:
SUBSTITUTED ACETOHYDRAZIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE
Document Type and Number:
WIPO Patent Application WO/2015/180583
Kind Code:
A1
Abstract:
Substituted acetohydrazide derivatives represented by formula I, or pharmaceutically acceptable salts thereof. The compounds and pharmaceutically acceptable salts of formula I effectively inhibit prolyl hydroxylase, and have stable hypoxia-inducible factor HIF-α activity.
Inventors:
LI SONG (CN)
XIAO JUNHAI (CN)
WANG LILI (CN)
LONG LONG (CN)
LI WEI (CN)
LUO HAOMING (CN)
LI FEIFEI (CN)
ZHONG WU (CN)
ZHENG ZHIBING (CN)
XIE YUNDE (CN)
LI XINGZHOU (CN)
ZHOU XINBO (CN)
WANG XIAOKUI (CN)
CAO RUIYUAN (CN)
XIAO JUNHAI (CN)
WANG LILI (CN)
LONG LONG (CN)
LI WEI (CN)
LUO HAOMING (CN)
LI FEIFEI (CN)
ZHONG WU (CN)
ZHENG ZHIBING (CN)
XIE YUNDE (CN)
LI XINGZHOU (CN)
ZHOU XINBO (CN)
WANG XIAOKUI (CN)
CAO RUIYUAN (CN)
Application Number:
PCT/CN2015/079370
Publication Date:
December 03, 2015
Filing Date:
May 20, 2015
Export Citation:
Assignee:
INST PHARM & TOXICOLOGY AMMS (CN)
International Classes:
C07C251/86; A61K31/165; A61K31/277; A61P7/06; A61P7/08; C07C249/16; C07C253/30; C07C255/58
Domestic Patent References:
| WO2003078386A1 | 2003-09-25 | |||
| WO2005037773A1 | 2005-04-28 | |||
| WO2009155362A1 | 2009-12-23 | |||
| WO2004108121A1 | 2004-12-16 |
Other References:
See also references of EP 3150576A4
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
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