SUBSTITUTED AMINO COMPOUNDS AND USE THEREOF - TAKEDA CHEMICAL INDUSTRIES LTD

Title:

SUBSTITUTED AMINO COMPOUNDS AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2004/014843

Kind Code:

A1

Abstract:

Compounds represented by the general formula (I) and β-secretase inhibitors containing the same: (I) wherein A is an aromatic ring which may have a substituent; R₁ is aryl-C_0-6alkyl, heteroaryl-C_0-6 alkyl, C_1-6 alkyl, or the like, each being optionally substituted; R₂ is hydrogen, optionally substituted aryl-C_0-6alkyl or heteroaryl-C_0-6 alkyl, or the like; R₃ is aryl-C_0-6alkyl, heteroaryl-C_0-6 alkyl, C_2-10 alkyl, or the like, each being optionally substituted; X and Y are each oxygen or the like; and each linkage represented by both a solid line and a broken line represents a single or double bond.

Inventors:

UCHIKAWA OSAMU (JP)
ASO KAZUYOSHI (JP)
KOIKE TATSUKI (JP)
TARUI NAOKI (JP)
HIRAI KEISUKE (JP)

Application Number:

PCT/JP2003/010045

Publication Date:

February 19, 2004

Filing Date:

August 07, 2003

Export Citation:

Click for automatic bibliography generation Help

Assignee:

TAKEDA CHEMICAL INDUSTRIES LTD (JP)
UCHIKAWA OSAMU (JP)
ASO KAZUYOSHI (JP)
KOIKE TATSUKI (JP)
TARUI NAOKI (JP)
HIRAI KEISUKE (JP)

International Classes:

A61K31/166; A61K31/18; A61K31/381; A61K31/41; A61K31/4409; A61K31/455; A61K31/55; A61P9/00; A61P9/10; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P43/00; C07C233/78; C07C311/16; C07D333/20; (IPC1-7): C07C233/78; A61K31/166; A61K31/18; A61K31/381; A61K31/41; A61K31/4409; A61K31/445; A61K31/455; A61K31/55; A61P9/00; A61P9/10; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P43/00; C07C235/50; C07C235/84; C07C237/34; C07C237/42; C07C251/40; C07C255/57; C07C311/16; C07D211/14; C07D211/16; C07D213/81; C07D213/82; C07D257/04; C07D295/14; C07D295/18; C07D311/16; C07D333/20; C07D333/60

Domestic Patent References:

WO2002002512A2	2002-01-10
WO2002002505A2	2002-01-10
WO2001027085A1	2001-04-19
WO2003040096A2	2003-05-15
WO2003072535A2	2003-09-04

Attorney, Agent or Firm:

Kawamiya, Osamu (IMP Building 3-7 Shiromi 1-chome, Chuo-k, Osaka-shi Osaka, JP)

Download PDF:

View/Download PDF PDF Help

Previous Patent: ACYLATED ARYLCYCLOALKYLAMINES AND THEIR USE AS PHARMACEUTICALS

Next Patent: ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION