Title:
SUBSTITUTED BENZIMIDAZOLONE COMPOUND AND COMPOSITION COMPRISING THE SAME
Document Type and Number:
WIPO Patent Application WO/2017/133337
Kind Code:
A1
Abstract:
The present invention provides a substituted benzimidazolone compound and a composition comprising the same. The present invention discloses a substituted benzimidazolone compound represented by formula (I) and a pharmaceutical composition containing the compound, or a crystalline form, a pharmaceutically acceptable salt, a hydrate or a solvate, a stereoisomer, a prodrug or an isotopic variant thereof. The substituted benzimidazolone compound disclosed in the present invention and the composition comprising the compound have excellent inhibitory activity against 5HT2 receptors with better pharmacokinetic parameter characteristics, and can improve drug concentration of the compound in an animal body, so as to improve drug efficacy and safety.
Inventors:
WANG YIHAN (CN)
LI HUANYIN (CN)
LI HUANYIN (CN)
Application Number:
PCT/CN2016/111193
Publication Date:
August 10, 2017
Filing Date:
December 21, 2016
Export Citation:
Assignee:
SHENZHEN TARGETRX INC (CN)
International Classes:
C07D235/26; A61K31/496; A61P1/00; A61P3/04; A61P3/10; A61P7/02; A61P7/12; A61P9/00; A61P15/00; A61P25/00; C07B59/00
Domestic Patent References:
| WO1993003016A1 | 1993-02-18 |
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