Title:
Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
Document Type and Number:
WIPO Patent Application WO1992019617
Kind Code:
A3
Abstract:
The present invention provides dibenzoxazepine compounds of Formula I: which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Inventors:
HALLINAN E ANN (US)
HAGEN TIMOTHY JOSEPH (US)
HUSA ROBERT KNOL (US)
TSYMBALOV SOFYA (US)
LEE ALBERT (US)
VAN HOECK JEAN-PIERRE (BE)
HAGEN TIMOTHY JOSEPH (US)
HUSA ROBERT KNOL (US)
TSYMBALOV SOFYA (US)
LEE ALBERT (US)
VAN HOECK JEAN-PIERRE (BE)
Application Number:
PCT/US1992/003028
Publication Date:
December 10, 1992
Filing Date:
April 16, 1992
Export Citation:
Assignee:
SEARLE & CO (US)
HALLINAN E ANN (US)
HAGEN TIMOTYH JOSEPH (US)
HUSA ROBERT KNOL (US)
TSYMBALOV SOFYA (US)
LEE ALBERT C (US)
VAN HOECK JEAN-PIERRE (BE)
HALLINAN E ANN (US)
HAGEN TIMOTYH JOSEPH (US)
HUSA ROBERT KNOL (US)
TSYMBALOV SOFYA (US)
LEE ALBERT C (US)
VAN HOECK JEAN-PIERRE (BE)
International Classes:
A61K31/553; A61P1/12; A61K31/55; A61P3/02; A61P9/06; A61P11/00; A61P11/06; A61P13/00; A61P13/02; A61P15/00; A61P19/10; A61P25/00; A61P25/02; A61P25/08; A61P43/00; C07D267/20; C07D413/04; C07D413/12; C07D413/14; C07D417/12; (IPC1-7): C07D413/12; A61K31/55
Foreign References:
| US3624104A | 1971-11-30 | |||
| US3917649A | 1975-11-04 | |||
| GB1522003A | 1978-08-23 | |||
| US4704386A | 1987-11-03 |
Other References:
See also references of EP 0583421A1
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