Title:
SUBSTITUTED OXADIAZOLE CHEMICAL COMPOUND AND COMPOSITION CONTAINING SAID CHEMICAL COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/143874
Kind Code:
A1
Abstract:
Provided are a substituted oxadiazole chemical compound and composition containing said chemical compound and use thereof; said substituted oxadiazole chemical compound is the oxadiazole chemical compound as represented by formula (I), or its crystalline form, pharmaceutically acceptable salt, prodrug, stereoisomer, hydrate, or solvent compound. The disclosed substituted oxadiazole chemical compound and composition containing said chemical compound are capable of inhibiting indoleamine 2,3-dioxygenase; it also has better pharmacokinetic parameter attributes and is capable of improving the drug concentration of the chemical compound in an animal body, thus improving the therapeutic efficacy and safety of the drug.
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Inventors:
WANG YIHAN (CN)
LI HUANYIN (CN)
LI HUANYIN (CN)
Application Number:
PCT/CN2017/070279
Publication Date:
August 31, 2017
Filing Date:
January 05, 2017
Export Citation:
Assignee:
SHENZHEN TARGETRX INC (CN)
International Classes:
C07D271/08; A61K31/41; A61K31/4245; A61K39/395; A61P1/00
Domestic Patent References:
| WO2015119944A1 | 2015-08-13 | |||
| WO2014066834A1 | 2014-05-01 |
Foreign References:
| CN102164902A | 2011-08-24 | |||
| CN101932325A | 2010-12-29 |
Other References:
JIANG, WENFENG ET AL.: "daoldai4 zuo4yong4 zai4 yao4wu4 yan2jiul zhongldel yinglyong4", QILU PHARMACEUTICAL AFFAIRS, vol. 29, no. 11, 31 December 2010 (2010-12-31), pages 682, XP008173943
See also references of EP 3398942A4
See also references of EP 3398942A4
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