Title:
SUBSTITUTED PHENOL COMPOUNDS USEFUL FOR ANESTHESIA AND SEDATION
Document Type and Number:
WIPO Patent Application WO2003026632
Kind Code:
A3
Abstract:
The invention provides substituted phenol compounds and pharmaceutical compositions containing substituted phenol compounds which are useful for inducing or maintaining anesthesia or sedation in a mammal. This invention also provides methods for inducing or maintaining anesthesia or sedation in a mammal using substituted phenol compounds.
Inventors:
JENKINS THOMAS E (US)
JI YU-HUA (US)
WU HUIWEI (US)
BOLTON JENNIFER (US)
JI YU-HUA (US)
WU HUIWEI (US)
BOLTON JENNIFER (US)
Application Number:
PCT/US2002/030477
Publication Date:
August 21, 2003
Filing Date:
September 26, 2002
Export Citation:
Assignee:
THERAVANCE INC (US)
JENKINS THOMAS E (US)
JI YU-HUA (US)
WU HUIWEI (US)
BOLTON JENNIFER (US)
JENKINS THOMAS E (US)
JI YU-HUA (US)
WU HUIWEI (US)
BOLTON JENNIFER (US)
International Classes:
A61K31/095; A61K31/165; A61K31/216; A61K31/66; A61K45/06; A61P23/00; C07C37/00; C07C39/19; C07C45/68; C07C45/71; C07C69/732; C07C69/88; (IPC1-7): C07C69/732; C07C69/88; A61P23/00; A61K31/216
Domestic Patent References:
| WO2001026656A2 | 2001-04-19 |
Foreign References:
| US3790648A | 1974-02-05 | |||
| US3808296A | 1974-04-30 | |||
| US3887638A | 1975-06-03 | |||
| JPS61218558A | 1986-09-29 | |||
| US5510361A | 1996-04-23 | |||
| US5155122A | 1992-10-13 |
Other References:
TRAPANI G ET AL: "Propofol Analogs. Synthesis, Relationships between Structure and Affinity at GABAA Receptor in Rat Brain, and Differential Electrophysiological Profile at Recombinant Human GABAA Receptors", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 41, 1998, pages 1846 - 1854, XP002112861, ISSN: 0022-2623
Download PDF: