Title:
SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2023/121184
Kind Code:
A1
Abstract:
The present invention relates to: a substituted thiazolidinedione derivative compound having a novel structure acting as a sterol regulatory element-binding protein-1 (SREBP1) inhibitor, a hydrate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating cancer, comprising same as an active ingredient.
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Inventors:
KIM JUN-KYUM (KR)
CHOI JIA (KR)
KIM EUN-JUNG (KR)
PARK CHEOL-KYU (KR)
HAM SEOK WON (KR)
PARK MIN GI (KR)
JEONG HYEON JU (KR)
KIM SUNG JIN (KR)
MIN KYUNGIM (KR)
PARK JONG MIN (KR)
CHIN JUNGWOOK (KR)
CHO SUNG JIN (KR)
KIM JINA (KR)
JUNG KYUNG JIN (KR)
KIM NAYEON (KR)
KIM SUHUI (KR)
KWON SUGYEONG (KR)
LEE SU-JEONG (KR)
JEONG MINSEON (KR)
AN HONGCHAN (KR)
PARK JEONG-EUN (KR)
KIM DONG-HYUN (KR)
LIM JI-YOUN (KR)
MIN JU-SIK (KR)
HWANG JI SUN (KR)
CHOI HYO-JUNG (KR)
HWANG HAYOUNG (KR)
KWON OH-BIN (KR)
LEE SUNGWOO (KR)
KIM SANG BUM (KR)
CHOI JIA (KR)
KIM EUN-JUNG (KR)
PARK CHEOL-KYU (KR)
HAM SEOK WON (KR)
PARK MIN GI (KR)
JEONG HYEON JU (KR)
KIM SUNG JIN (KR)
MIN KYUNGIM (KR)
PARK JONG MIN (KR)
CHIN JUNGWOOK (KR)
CHO SUNG JIN (KR)
KIM JINA (KR)
JUNG KYUNG JIN (KR)
KIM NAYEON (KR)
KIM SUHUI (KR)
KWON SUGYEONG (KR)
LEE SU-JEONG (KR)
JEONG MINSEON (KR)
AN HONGCHAN (KR)
PARK JEONG-EUN (KR)
KIM DONG-HYUN (KR)
LIM JI-YOUN (KR)
MIN JU-SIK (KR)
HWANG JI SUN (KR)
CHOI HYO-JUNG (KR)
HWANG HAYOUNG (KR)
KWON OH-BIN (KR)
LEE SUNGWOO (KR)
KIM SANG BUM (KR)
Application Number:
PCT/KR2022/020728
Publication Date:
June 29, 2023
Filing Date:
December 19, 2022
Export Citation:
Assignee:
MEDIFIC INC (KR)
International Classes:
C07D417/06; A61K31/4439; A61P35/00
Domestic Patent References:
| WO2002072009A2 | 2002-09-19 | |||
| WO2017176040A1 | 2017-10-12 |
Foreign References:
| US20040214872A1 | 2004-10-28 | |||
| US9056862B2 | 2015-06-16 |
Other References:
HELMSTÄDTER MORITZ, VIETOR JAN, SOMMER JANA, SCHIERLE SIMONE, WILLEMS SABINE, KAISER ASTRID, SCHMIDT JUREMA, MERK DANIEL: "A New FXR Ligand Chemotype with Agonist/Antagonist Switch", ACS MEDICINAL CHEMISTRY LETTERS, AMERICAN CHEMICAL SOCIETY, US, vol. 12, no. 2, 11 February 2021 (2021-02-11), US , pages 267 - 274, XP093073799, ISSN: 1948-5875, DOI: 10.1021/acsmedchemlett.0c00647
Attorney, Agent or Firm:
PLUS INTERNATIONAL IP LAW FIRM (KR)
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